Publications by authors named "Irene Dolz-Perez"
Article Synopsis
- After a heart attack, a treatment called coronary angioplasty can cause some damage to the heart, known as ischemia-reperfusion (I/R) injury.
- Omega-3 fatty acids (PUFAs) can help protect the heart, but scientists found a way to make them work better using a special compound called poly-l-glutamic acid (PGA).
- By combining PGA with a specific omega-3 fatty acid (diDHA), it helps protect heart cells from damage and could lead to better treatments for patients after heart surgeries.
Topical treatment of mild-to-moderate psoriasis with corticosteroids suffers from challenges that include reduced drug bioavailability at the desired site of action. The retention of therapeutics within the epidermis can safely treat skin inflammation, scaling, and erythema associated with psoriasis while avoiding possible side effects associated with systemic treatments. We successfully synthesized and characterized a pH-responsive biodegradable poly-L-glutamic acid (PGA)-fluocinolone acetonide (FLUO) conjugate that allows the controlled release of the FLUO to reduce skin inflammation.
View Article and Find Full Text PDF