Publications by authors named "Irene Bianco"

Article Synopsis
  • Human breast milk (HBM) is the best nutrition for infants, helping prevent infections and chronic diseases by positively influencing their gut microbiota.
  • The composition of beneficial microbes in HBM is varied and influenced by factors like gestational age, delivery method, and maternal lifestyle choices such as diet and stress.
  • Research highlights the need for better understanding of maternal lifestyle effects on HBM microbiota to develop strategies for improving infant gut health.
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  • * The update reflects new studies that reinforce the effectiveness of ECP in treating GVHD, with the goal of establishing consistent criteria for its use in both adults and children across Italy while ensuring patient safety and high-quality care.
  • * The guideline development involved a diverse group of specialists, including transfusionists and hematologists, with oversight by a hematologist skilled in systematic reviews, and also included input from a patient representative
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  • This study looked at how pregnant women's eating habits and lifestyle choices affect their weight gain during pregnancy.
  • It found that not gaining enough weight can be linked to factors like education level and how much they ate, especially vegetables.
  • The results suggest that making healthy food choices, like eating more veggies and less meat, can help keep both moms and babies healthier during pregnancy.
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COVID19 convalescent patient plasma units with high titer neutralizing antibody can be used to treat patients with severe disease. Therefore, in order to select suitable donors, neutralizing antibody titer against SARS CoV-2 needs to be determined. Because the neutralization assay is highly demanding from several points of view, a pre-selection of sera would be desirable to minimize the number of sera to be tested.

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Immunosuppressive medication dosing errors are not unfrequent and may present a number of challenges to transplant clinicians. Tacrolimus (TAC) is a widely used immunosuppressant with a narrow therapeutic index and potential severe side effects, including neurotoxicity and kidney injury. We herein report a case of 60-year-old woman who underwent deceased-donor liver transplantation at our center and due to inadvertent TAC overexposure was admitted to the Intensive Care Unit because of severe neurologic impairment, kidney injury and arterial hypotension.

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The aim of the present work was to assess the incidence of neuro-nephrotoxicity after a single-staggered dose of calcineurin inhibitors (CI) with different immunosuppressive approaches. From January to December 2006, all liver transplantation (LT) recipients at risk of renal or neurological complications treated with extracorporeal photopheresis (ECP) + mycophenolate mofetil + steroids and staggered introduction of CI (ECP group) were compared with a historical control group on standard CI-based immunosuppression. The ECP group included 24 patients with a mean model for end-stage liver disease (MELD) score of 19.

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Background: ABO-incompatible (ABO-i) liver transplantation (LT) is a high-risk procedure due to the potential for antibody-mediated rejection (AMR) and cell-mediated rejection. The aim of the current report is to illustrate the results of a retrospective comparison study on the use of immunomodulation with therapeutic plasma exchange (TPE) associated to high-dose immunoglobulins (IVIg) and extracorporeal photopheresis (ECP) in ABO-i adult LT patients.

Patients And Methods: Between January 1996 and December 2005, 19 patients underwent ABO-i LT.

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