Retrospective analysis of clinical and pathomorphological features of lupus nephritis in children.

Purpose: The aim of the study was to evaluate the clinical course and pathomorphological correlations in Polish children with the diagnosis of lupus nephritis (LN).

Methods: We retrospectively analyzed the medical records of 39 children hospitalized due to LN in 7 pediatric nephrology units in Poland between 2010 and 2019. Demographic data, clinical symptoms at the onset of LN and laboratory parameters were reviewed.

[Prune-belly syndrome and therapeutic problems].

Unlabelled: Specific features of Prune-Belly syndrome (PBS) are deficiency of the abdominal muscles, urinary abnormalities and cryptorchidism. Diagnostics is possible prenatally. In order to inhibit kidney degradation process "in utero" intervention are performed.

[Prognostic factors in children with lupus nephritis].

Renal involvement in systemic lupus erythematosus in children is very often observed. Clinical manifestation of nephropathy has been detected in 70% of patients. Lupus nephritis (LN) has a recurrent course and remains a cause of chronic renal failure.

[Evaluation of renal function in children undergoing surgery under general anaesthesia].

Unlabelled: 47 children (29 boys and 18 girls) aged from 3 to 13 years were examined. The children were operated under general anaesthesia. All children were in good general condition, belonged to anaesthesia risk groups ASA 1 and ASA 2, had no metabolic, endocrinological, haematological diseases nor had renal or hepatic dysfunction.

Analysis of collagen IV and fibronectin in blood and urine in evaluation of nephrotic fibrosis in children with chronic glomerulonephritis.

Background: Changes in the concentration of extracellular matrix components in body fluids may reflect the degree of kidney fibrosis. The aim of our study was to evaluate fibronectin (FN) and type IV collagen (COL IV) concentrations in blood serum and urine, and to refer these values to immunoreactivity in renal biopsy material.

Material/methods: Our research involved 37 children with glomerulonephritis (GN) aged 4-15 and 18 healthy children.