Publications by authors named "Irena Slaveska Spirevska"
Article Synopsis
- The study focuses on a method to measure trans-resveratrol and vitamin E in dietary supplements, emphasizing the need for product quality verification.
- A high-throughput HPLC/UV method was developed and validated, demonstrating good sensitivity, accuracy, and low environmental impact, as confirmed by eco-scale assessments.
- The method offers a quick analysis time of 7 minutes and is suitable for inline quality control, making it practical for use in dietary supplement testing.
Concepts and principles for new rapid simple liquid chromatography method for quantification of antioxidants resveratrol, vitamin E, and coenzyme Q10 in capsules with high-performance liquid chromatography with a photo-diode array detector.
J Sep Sci
January 2024
Principles and problems in the development of simultaneous liquid chromatography (LC) analytical methods for potent antioxidative molecules resveratrol, tocopherol, and coenzyme Q10 in capsules, have been investigated and systematically compared and summarized. For these purposes, experiments within the full polarity spectrum of LC techniques. were tested and recorded.
View Article and Find Full Text PDFA unique approach for in-situ monitoring of the THCA decarboxylation reaction in solid state.
Spectrochim Acta A Mol Biomol Spectrosc
February 2022
The decarboxylation of Δ9-tetrahydrocannabinolic acid (THCA) plays pivotal role in the potency of medical cannabis and its extracts. Our present work aims to draw attention to mid-infrared (MIR) spectroscopy to in-situ monitor and decipher the THCA decarboxylation reaction in the solid state. The initial TG/DTG curves of THCA, for a first time, outlined the solid-solid decarboxylation dynamics, defined the endpoint of the process and the temperature of the maximal conversion rate, which aided in the design of the further IR experiment.
View Article and Find Full Text PDF