Medicina (Kaunas)
February 2022
: Edentulism is considered to be an impediment impacting both patients' quality of life and their nutrition. Conventional complete dentures are still a preferred treatment. However, there is no consensus on the most important factors which could substantially reduce the risk of patient dissatisfaction.
View Article and Find Full Text PDFThis multicenter study aimed at comparing different techniques of lip and nose repair with or without NAM and primary anterior rhinoplasty in pre-adolescent children. Patients with unilateral clefts of lip, alveolus, and palate who had undergone cleft lip and nose repair were evaluated in a prospective three-centre study using standardized monochromatic, cropped photographs. Four cleft surgeons evaluated the aesthetics of the central part of the face when the patients had reached age ten years.
View Article and Find Full Text PDFOn October 24, 2019, a marketing authorization valid through the European Union (EU) was issued for gilteritinib monotherapy for adult patients who have relapsed or refractory acute myeloid leukemia (AML) with an Fms-like tyrosine kinase 3 (FLT3) mutation. Gilteritinib inhibits FLT3 receptor signaling and proliferation in cells exogenously expressing FLT3 including FLT3 internal tandem duplication (ITD), FLT3 D835Y, and FLT3 ITD D835Y, and it induced apoptosis in leukemic cells expressing FLT3 ITD. The recommended starting dose of gilteritinib is 120 mg (three 40 mg tablets) once daily.
View Article and Find Full Text PDFDespite the numerous industrially manufactured medicines available in the market, extemporaneously prepared drugs still have their niche among the services offered by the pharmacies. The physicians prescribe extemporaneously prepared drugs for special patient groups that require custom approach. Therefore, physicians' knowledge about extemporaneously prepared drugs and experience in prescribing them is the main precondition for satisfying patients' needs.
View Article and Find Full Text PDFBACKGROUND. The need for appraisal of oral health-related quality of life has been increasingly recognized over the last decades. The aim of this study was to develope a Latvian and a Russian version and test the validity of the Oral Health Impact Profile (OHIP-49) for use among adults in Latvia.
View Article and Find Full Text PDFUnlabelled: The condyle has a special multidirectional capacity for the growth and adaptive remodeling of temporomandibular joint (TMJ). Being part of TMJ structure, it plays an important role in the stability of long-term treatment results for orthodontic and orthognatic patients with Class II division 1 subdivision malocclusions. Several computed tomography (CT) investigation modes have been used to evaluate the craniofacial morphology and particularly, for TMJ.
View Article and Find Full Text PDFEvidence based clinical studies have shown exact recommended design for artificial crown reconstruction with acceptable long-term results taking into an account the biological price. Previous histological and clinical studies proved that fixed prostheses might influence the periodontal condition of crowned teeth, if not all biological criteria have been considered. The aim of the present study was to assess the periodontal condition of the crowned teeth after stainless steel swaged crowns were replaced by cast metal ceramic crowns.
View Article and Find Full Text PDFAwareness of the age related situation as to the malocclusion prevalence in population and orthodontic treatment need is very important and useful for planning an orthodontic care, especially taking into account the interdisciplinary aspect of the problem. The aim of this study was to investigate the degree of severity of malocclusion and the need of orthodontic treatment in three different age groups of population in Latvia. The study group comprised samples of 12-13-yr-olds (n=46), 18-yr-olds (n=32) and 35-44-yr-olds (n=278).
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