Publications by authors named "Irena Ilic"

Background: Esophageal cancer is a major public health issue, yet risk factors for its occurrence are still insufficiently known. This study aimed to estimate the global burden of esophageal cancer and its risk factors.

Methods: This ecological study presented the incidence, mortality, and Disability-Adjusted Life Years (DALYs) of esophageal cancer in the world.

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  • Alzheimer’s disease and other dementias are significant global health issues, and this study focused on their connection to high fasting plasma glucose over recent decades.
  • In 2021, there were approximately 2 million deaths due to these conditions, with about 290,000 fatalities linked specifically to high fasting plasma glucose, showing notable gender disparities.
  • The study found a substantial increase in the mortality and Disability-Adjusted Life Years (DALYs) related to these conditions from 1990 to 2021, particularly in regions like High-income North America and Central Asia, with significant statistical findings indicating age and period effects.
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Introduction: Women who receive a result of an abnormal Papanicolaou (Pap) smear can fail to participate in follow up procedures, and this is often due to anxiety. This study aimed to apply artificial neural networks (ANN) in prediction of anxiety in women with an abnormal Pap smear test, prior to and following diagnostic procedures.

Methods: One hundred-seventy two women who received an abnormal Pap screening result took part in this study, completing a questionnaire about socio-demographic characteristics and Hospital Anxiety and Depression Scale (HADS), right before and two to four weeks after diagnostics (i.

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: This study aimed to evaluate psychosocial burden and its associated factors in women who were referred for additional diagnostic procedures following receipt of a positive cervical-cancer-screening smear result. : A cross-sectional study was performed in a consecutive cohort of only women who received an abnormal Papanicolaou screening result and therefore presented to a gynecologist for additional diagnostic examinations (colposcopy/biopsy/endocervical curettage) at the Clinic for Gynecology and Obstetrics of the Clinical Center. Multivariate linear regression was used for data analysis, with Bonferroni correction applied for multiple comparisons.

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(1) Background: Cervical screening and additional diagnostic procedures often lead to depression. This research aimed to develop a prediction model for depression in women who received an abnormal Papanicolaou screening test, prior to and following the diagnostic procedures. (2) Methods: The study included women who had a positive Papanicolaou screening test (N = 172) and attended the Clinical Center of Kragujevac in Serbia for additional diagnostic procedures (colposcopy/biopsy/endocervical curettage).

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Background: Although burnout syndrome has been described in numerous research studies, the data on burnout syndrome among medical students in developing countries is scanty. This study aimed to determine the prevalence of high-risk for burnout syndrome and its associated factors among university undergraduate medical students in Serbia.

Methods: An observational, analytical, cross-sectional study was conducted using the Maslach Burnout Inventory-Student Survey and a survey on associated factors.

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: infection is a major public health issue, being among the main causes of mortality due to healthcare-associated diarrhea. This study aimed to assess the trends in mortality attributable to infections in European countries over a period of 30 years. : A descriptive epidemiological study was conducted, with the application of an ecological study design, to evaluate the trends in mortality due to infection in the Central, Eastern, and Western European sub-regions from 1990 to 2019.

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Introduction: Although research on burnout syndrome in medical students has increased in recent years, results are inconsistent about which factors are associated with a high risk for burnout syndrome. The aim of this study was to assess the prevalence of high risk of burnout syndrome and to identify factors associated with burnout in medical students in preclinical and clinical training.

Method: A cross-sectional study was conducted at the University of Kragujevac, Serbia.

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: Dengue is an important public health concern that warrants an examination of the longer-term global trends of its disease burden. The aim of this study was to assess the trends in dengue incidence and mortality worldwide over the last three decades. : A descriptive epidemiological study was carried out, investigating the trends in the incidence and mortality of dengue from 1990 to 2019.

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(1) Background: This study aimed to assess the global burden of pancreatic cancer attributable to a high BMI in 1990-2019. (2) Methods: An ecological study was carried out. Data about deaths and Disability-Adjusted Life Years (DALYs) for pancreatic cancer were extracted from the Global Burden of Disease (GBD) study.

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Background: Previous studies suggest that trends of cancer of colon, rectum and anus (CRA) incidence and mortality have been decreasing in recent decades. However, the trends are not uniform across age groups. This study aimed to assess the trends of the cancer of CRA burden worldwide.

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  • The study examines hip fractures caused by falls in Central Europe from 1990 to 2019, revealing a notable burden, especially in older adults.
  • About 400,000 new hip fracture cases due to falls were recorded in 2019, with males at 220,000 and females at 160,000, significantly impacting quality of life as indicated by YLDs.
  • Interestingly, while female incidence rates of hip fractures due to falls have decreased, male rates have risen slightly, highlighting the need for continued attention to this health issue.
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When hypostatic pneumonia is present at the same time as COVID-19 pneumonia, the clinical course is almost always prolonged (prolonged-COVID-19) due to persistent inflammation, long-term anti-inflammatory syndrome, followed by immune exhaustion, i.e., by immunosuppression and catabolic syndrome.

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  • Lip, oral, and pharyngeal cancers pose significant global health challenges, making it essential to analyze their burden for effective health policies.
  • The study utilized data from the 2019 Global Burden of Diseases, Injuries, and Risk Factors Study to assess cancer incidence, mortality, and life years lost across 204 countries, linking these to socio-demographic factors.
  • Findings revealed approximately 370,000 cases and 199,000 deaths for lip and oral cavity cancer, and 167,000 cases and 114,000 deaths for other pharyngeal cancers in 2019, with smoking being the leading risk factor for these cancers, especially in low and middle SDI regions.
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Background: Atopic dermatitis is a major public health issue worldwide, but data on trends in prevalence in children in European countries are sparse. The aim of this study was to assess the trends in the prevalence of atopic dermatitis in children under 5 in the Central, Eastern, and Western European sub-regions from 1990 to 2019.

Methods: In this study, a descriptive, observational epidemiological method was applied.

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Objective: Women often experience psychological distress upon receipt of an abnormal Pap test result. This study aimed to evaluate psychological distress and its correlates among women who received an abnormal Pap screening test result.

Material And Methods: A cross-sectional study was performed in a cohort of 172 consecutive women who had attended screening for cervical cancer and who received abnormal Pap smear results and underwent additional diagnostic procedures (colposcopy/biopsy/endocervical curettage).

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Background: Brain cancer is a serious issue in the global burden of diseases. This observational research aimed to assess trends of the brain cancer incidence and mortality in the world in the period 1990-2019.

Methods: Brain cancer incidence and mortality data were retrieved from the Global Burden of Disease 2019 study database.

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Diabetes mellitus (DM) is among the major global public health issues. According to recent projections, a continued rise in DM prevalence is expected in the following decades. The research has shown that DM is associated with poorer outcomes of coronavirus disease 2019 (COVID-19).

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The burnout syndrome may affect academic achievement, but research on burnout and academic success of medical students is sparse. This research aimed to estimate the prevalence of high risk of burnout in students of medicine and to investigate its association with academic performance. It included 760 full-time medical students who completed the survey (response rate = 90.

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Background: Cholera is a large public health issue, especially in countries with limited resources. The aim of the study was to determine trends in global cholera mortality from 1990-2019.

Methods: This research is an observational, descriptive epidemiological study.

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Aim: To describe epidemiological characteristics of multi-country outbreak of severe acute hepatitis of unknown origin in children in 2022.

Methods: A descriptive epidemiological study design was used. The review based on the available information concerning this multi-country outbreak aims to summarise the current knowledge about the severe acute hepatitis of unknown origin in children, highlights the suggested working hypotheses, introduces some of the potential explanations for its occurrence and reports on public health measures undertaken to control the disease.

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  • This review looked at how researchers in Europe study the concept of disability-adjusted life years (DALY) for infectious diseases.
  • They found 105 studies that met their criteria, with most focusing on food- and water-borne diseases.
  • The number of these studies has grown, particularly from 2015 to 2022, and there's a need for better guidelines to help make results more comparable.
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  • HIV/AIDS remains a significant public health issue in sub-Saharan Africa, with current efforts falling short of global targets for eradication set by UNAIDS and the SDGs.
  • The study utilized extensive data from various HIV prevalence surveys to estimate localized HIV infection rates across 43 African countries, focusing on specific age and sex groups from 2000 to 2018.
  • Findings revealed wide disparities in HIV prevalence within countries and districts, indicating that age and sex stratification provides more nuanced insights into the epidemic, which can help tailor prevention and treatment efforts more effectively.
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Pancreatic cancer represents a serious public health problem worldwide. Due to its high mortality, efforts on identifying risk factors are very important since only a few risk-related factors have been well established. The present study aimed to address this knowledge gap by estimating the risk of pancreatic cancer associated with opium use.

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Background: Human monkeypox was a neglected zoonotic disease considered endemic to rainforests of rural parts of Central and Western Africa, until a global outbreak in May 2022.

Methods: This review describes the epidemiological characteristics of human monkeypox.

Results: Since the first confirmed case in the United Kingdom on 13 May 2022, and up until 19 September, more than 62,000 cases of human monkeypox were reported in 104 countries in the world (among them 97 countries where the monkeypox virus was not endemic).

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