Publications by authors named "Irem Melike Yazicioglu"
Article Synopsis
- Idiopathic granulomatous mastitis (IGM) is a rare breast inflammation with a high chance of returning after treatment, and this study explores the serum albumin to globulin ratio (AGR) as a possible predictor for its recurrence.
- A retrospective analysis included 85 patients diagnosed with IGM from 2016 to 2021, revealing that 18.8% experienced a recurrence; the results showed a significant correlation between lower AGR levels and increased recurrence risk.
- The study concludes that a low AGR (≤1.179) and smoking are notable risk factors for IGM recurrence, suggesting that incorporating AGR into risk assessments could improve treatment outcomes for patients.
Objective: The aim of the study was to evaluate the effect of systemically administrated curcumin on the prevention of peridural fibrotic tissue and adhesion formation in a rat laminectomy model.
Methods: Thirty-two Wistar albino rats were randomly selected and equally divided into 4 groups as follows: negative control group (group I) did not undergo operation; positive control group (group II) underwent laminectomy without treatment; group III (low-dose curcumin; 100 mg/kg); and group IV (high-dose curcumin; 200 mg/kg). Curcumin was administered intraperitoneally per day for 7 days after surgery starting from day 0.