Publications by authors named "Irda Fidrianny"

Free radicals are inhibited by antioxidant compounds, which can be naturally sourced from soursop ( L.). Extraction processes affect levels of antioxidant compounds in the extract.

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<b>Background and Objective:</b> Pepino (<i>Solanum muricatum</i> Aiton), rich with vitamin C and flavonoids, constitutes an abundant source of potent antioxidants. This research was conducted to determine antioxidant activity from three different parts of pepino based on equivalence with ascorbic acid, to analyze the relationship between total phenolic content (TPC) and total flavonoid content (TFC) on antioxidant activities and to determine flavonoid compounds. <b>Materials and Methods:</b> Antioxidant activities were determined using 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) and Cupric Ion Reducing Antioxidant Capacity (CUPRAC) methods.

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This study aimed to characterize chitin extracted from Indonesia mangrove crab () shells, as well as to assess its cytotoxic, antioxidant, and HMG CoA reductase inhibitory potentials. molecular docking, molecular dynamic, and ADMET prediction analyses were also carried out. Chitin was extracted from mangrove crab shells using deproteination and demineralization processes, Scanning Electron Microscopy (SEM) and Fourier Transform Infrared (FTIR) characterization are then performed.

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Article Synopsis
  • The study focuses on an endemic plant from North Sumatera, Indonesia, known for its antioxidant and antibacterial properties.
  • Researchers analyzed the antioxidant and antibacterial activities of the plant's leaves, barks, twigs, and fruits, using several scientific methods.
  • Results showed that the bark extract had the highest antioxidant capacity and effectively inhibited six out of nine pathogenic bacteria, suggesting its potential for development as a therapeutic agent.
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This study aims to determine the antiobesity activity of leaves extract (CSLE) on high fat diet-fed rats (HFD) and to predict the molecular docking and pharmacokinetics of selected compounds of to fat mass and obesity-associated protein (FTO). Daily body weight, organ, carcass fat (renal and anal), body mass index, total cholesterol, and total triglyceride levels were observed after CSLE was given orally for 50 days. Furthermore, body mass index of a CSLE dose of 50 mg/kgbw, 100 mg/kgbw and orlistat (120 mg/kgbw) group are 0.

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We developed a facile preparation method of oil-in-water (O/W) Pickering emulsion in an emollient formulation using basil extract ( L.) as a solid particle stabilizer by fine-tuning the concentration and mixing steps of common cosmetic formulas, such as humectants (hexylene glycol and glycerol), surfactant (Tween 20), and moisturizer (urea). The hydrophobicity of the main phenolic compounds of basil extract (BE), namely, salvigenin, eupatorin, rosmarinic acid, and lariciresinol, supported high interfacial coverage to prevent coalescence of globules.

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<b>Background and Objective:</b> Antioxidants are substances that can deactivate free radicals. Phenol and flavonoid are antioxidant compounds widely found in plants, including purple sweet potato (<i>Ipomoea batatas</i> L.).

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Background: Banana (Musa sp.) is a plant rich in phytochemical compounds, especially antioxidants, which are hypothesized to inhibit the activity of acetylcholinesterase, an enzyme associated with Alzheimer's Disease.

Objective: This research aimed to study nanoemulsion preparations of Kepok banana (KEP-NE) and Tanduk banana (TAN-NE) peel extracts for their activities as antioxidants, acetylcholinesterase as well as tyrosinase inhibitors, and as agents to improve short-term memory.

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Free radicals can cause many diseases, such as cancer. Antioxidant is a compound that could scavenge free radicals. One of the natural antioxidants is guava.

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Objectives: Honey is an apiary product with various medicinal properties resulting from its bioactive compounds. Here, we aimed to determine the antioxidant and antibacterial properties of the Indonesian honey extracts and their correlation with total phenolic content (TPC) and total flavonoid content (TFC).

Methods: We extracted ethyl acetate-n-hexane and two types of ethanolic extracts from crude honey.

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Objectives: In this study, we aimed to determine the antioxidant activities of two varieties of sesame ( L.) seeds using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), and ferric reducing antioxidant power (FRAP) method, and to investigate the correlation between total phenolic as well as flavonoid contents and antioxidant activities of the extracts.

Methods: The antioxidant activities were determined using DPPH, ABTS, and FRAP assays, and the total phenolic content (TPC) and total flavonoid content (TFC) were measured by ultraviolet (UV)-Vis spectrophotometry.

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and are the major skin bacteria that cause the formation of acne. The present study was conducted to investigate antibacterial activity of ethanolic extract of cinnamon bark, honey, and their combination against acne bacteria. The antibacterial activity of extract of cinnamon bark and honey were investigated against and using disc diffusion.

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Temu kunci (Kaempferia pandurata (Roxb.)) has a number of benefits and one of these is antibacterial. The rhizome is said to have antibacterial activity against Streptococcus mutans, Lactocillus sp.

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