Reminding Peer Reviewers of Reporting Guideline Items to Improve Completeness in Published Articles: Primary Results of 2 Randomized Trials.

Importance: Numerous studies have shown that adherence to reporting guidelines is suboptimal.

Objective: To evaluate whether asking peer reviewers to check if specific reporting guideline items were adequately reported would improve adherence to reporting guidelines in published articles.

Design, Setting, And Participants: Two parallel-group, superiority randomized trials were performed using manuscripts submitted to 7 biomedical journals (5 from the BMJ Publishing Group and 2 from the Public Library of Science) as the unit of randomization, with peer reviewers allocated to the intervention or control group.

Preprints as a driver of open science: Opportunities for Southeast Asia.

Southeast Asia is an emerging force of open access scholarly output. For example, Indonesia is in a tight competition with United Kingdom as the largest publisher of open access journals and the second largest producer of open access articles in the world (according to DOAJ and the COKI OA Dashboard, respectively). However, this support for open practices is not yet reflected in institutional research policies in Southeast Asian countries, which still rely on criteria influenced by world university rankings that focus on publication outputs and do not incorporate elements related to research culture, integrity, or open science.

A guide to preprinting for early-career researchers.

The use of preprints, research manuscripts shared publicly before completing the traditional peer-review process, is becoming a more common practice among life science researchers. Early-career researchers (ECRs) benefit from posting preprints as they are shareable, citable, and prove productivity. However, preprinting a manuscript involves a discussion among all co-authors, and ECRs are often not the decision-makers.

Recommendations for empowering early career researchers to improve research culture and practice.

Early career researchers (ECRs) are important stakeholders leading efforts to catalyze systemic change in research culture and practice. Here, we summarize the outputs from a virtual unconventional conference (unconference), which brought together 54 invited experts from 20 countries with extensive experience in ECR initiatives designed to improve the culture and practice of science. Together, we drafted 2 sets of recommendations for (1) ECRs directly involved in initiatives or activities to change research culture and practice; and (2) stakeholders who wish to support ECRs in these efforts.

Promoting constructive feedback on preprints with the FAST principles.

Ensuring that public feedback on preprints is focused, appropriate, specific and transparent (or FAST) will help to develop a thriving culture for reviewing and commenting on preprints.

Responsible handling of ethics in data publication.

A global working group has developed recommendations for the responsible handling of the growing range of ethics cases related to data publication, but further community work is needed toward a responsible and cohesive data publishing ecosystem.

Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial.

Introduction: Transparent and accurate reporting is essential for readers to adequately interpret the results of a study. Journals can play a vital role in improving the reporting of published randomised controlled trials (RCTs). We describe an RCT to evaluate our hypothesis that asking peer reviewers to check whether the most important and poorly reported CONsolidated Standards of Reporting Trials (CONSORT) items are adequately reported will result in higher adherence to CONSORT guidelines in published RCTs.

A recombinant H1 histone-based system for efficient delivery of nucleic acids.

We describe here a unique transfer system based on a truncated form of the human linker histone H1F4 for the delivery of nucleic acids to a variety of cells. The efficiency of truncated histone H1.4F was assessed using both primary mammalian and immortalised insect and mammalian cell lines.