Socioeconomic and gender inequalities in mental disorders among adolescents and young adults.

Background: Socioeconomic status (SES) and gender play a key role in mental health. The objective of this study was to assess socioeconomic and gender mental health inequalities in adolescents and young adults using a population-based registry.

Materials And Methods: We conducted a lifetime follow-up study of all residents in the Basque Country between 1 and 30 years old (n=609,381) as of 31 December 2018.

Cost-utility analysis of the UPRIGHT intervention promoting resilience in adolescents.

Background: As mental health in adulthood is related to mental status during adolescence, school-based interventions have been proposed to improve resilience. The objective of this study was to build a simulation model representing the natural history of mental disorders in childhood, adolescence and youth to estimate the cost-effectiveness of the UPRIGHT school-based intervention in promoting resilience and mental health in adolescence.

Methods: We built a discrete event simulation model fed with real-world data (cumulative incidence disaggregated into eight clusters) from the Basque Health Service database (609,381 individuals) to calculate utilities (quality-adjusted life years [QALYs]) and costs for the general population in two scenarios (base case and intervention).

Incidence of mental disorders in the general population aged 1-30 years disaggregated by gender and socioeconomic status.

Purpose: The objective of this study was to estimate the incidence and age of onset of mental disorders diagnosed by gender and socioeconomic status (SES) in children, adolescents, and young adults up to 30 years of age in the whole population of the Basque Country (Spain).

Methods: All mental health diagnoses documented in Basque Health Service records from 1 January 2003 to 31 December 2018, were classified into eight clusters: anxiety, attention deficit hyperactivity disorder (ADHD), conduct disorders, depression, psychosis/personality disorders, substance use, eating disorders, and self-harm. We calculated incidence and cumulative incidence for each cluster, disaggregated by gender, and socioeconomic status (SES).

Relevance of well-being, resilience, and health-related quality of life to mental health profiles of European adolescents: results from a cross-sectional analysis of the school-based multinational UPRIGHT project.

Purpose: The existing evidence suggests that a complete evaluation of mental health should incorporate both psychopathology and mental well-being indicators. However, few studies categorize European adolescents into subgroups based on such complete mental health data. This study used the data on mental well-being and symptoms of mental and behavioral disorders to explore the mental health profiles of adolescents in Europe.

UPRIGHT, a resilience-based intervention to promote mental well-being in schools: study rationale and methodology for a European randomized controlled trial.

Background: Adolescence is crucial period for laying the foundations for healthy development and mental well-being. The increasing prevalence of mental disorders amongst adolescents makes promotion of mental well-being and prevention interventions at schools important. UPRIGHT (Universal Preventive Resilience Intervention Globally implemented in schools to improve and promote mental Health for Teenagers) is designed as a whole school approach (school community, students and families) to promote a culture of mental well-being and prevent mental disorders by enhancing resilience capacities.

Psoriasis: from gene to clinic.

The 5th International Congress "Psoriasis: From Gene to Clinic" took place in London, December 4-6, 2008, at The Royal College of Physicians. The understanding of psoriasis pathology has greatly transformed during the last few years. This transformation is due to the contribution of translational research, and gathering knowledge from clinical and basic research, in areas such as targeted biologicals in patients, wide gene expression analysis in cutaneous biopsies and identification of susceptibility genes to psoriasis.

Novelties in the treatment and management of thoracic disorders.

The 104th International Conference of the American Thoracic Society (ATS) was held in Toronto, Canada, May 16-21, 2008. The meeting brought together more than 15,000 scientists and clinicians worldwide and disclosed recent advances related to prevention, diagnosis, prognostic indicators or biomarkers of disease and treatment of thoracic disorders, including asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, pulmonary arterial hypertension, cystic fibrosis and sleep disorders. New future lines of investigation are now open and invite researchers to attend the next ATS conference in San Diego in 2009.