Publications by authors named "Irani do Carmo Francischetto Fin"
Association of PvuII and XbaI polymorphisms on estrogen receptor alpha (ESR1) gene to changes into serum lipid profile of post-menopausal women: Effects of aging, body mass index and breast cancer incidence.
Neuza Felix Gomes-Rochette Letícia Soncini Souza Bruno Otoni Tommasi Diego França Pedrosa Sérgio Ragi Eis Irani do Carmo Francischetto Fin
PLoS One
August 2017
Article Synopsis
- Estrogen plays a crucial role in regulating various functions in the female body, particularly in lipid metabolism and breast cancer.
- The study investigated two specific SNPs in the ESR1 gene and their effects on lipid levels and breast cancer incidence in post-menopausal Brazilian women over five years.
- Findings indicated that while one SNP (PvuII) was linked to lower body fat and lower breast cancer rates, the other (XbaI) was associated with higher triglyceride levels and a greater incidence of breast cancer in homozygous patients.