Publications by authors named "Iram Shahzadi"

The presence of toxic dyes in industrial waste dramatically diminishes the beneficial effects of remediation efforts. To overcome the hazardous impacts of dyes on biodiversity and environment, we integrated polymers into nanoparticles to substantially enhance their functionality and performance. 2 and 4 wt% of chitosan (CS) and 3 wt% of polyacrylic acid (PAA) doped cadmium selenide (CdSe) nanostructures (NSs) were prepared by co-precipitation approach.

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Article Synopsis
  • The study evaluates how the quality of computed tomography angiography (CTA) images, particularly those from Photon Counting Computed Tomography (PCCT), impacts the effectiveness of a deep learning (DL) algorithm in detecting large vessel occlusions (LVO) during acute ischemic stroke diagnostics.
  • 443 cases were analyzed, including both positive and negative occlusion cases, and the DL software prototype's performance was assessed with sensitivity and specificity metrics.
  • Results showed that the DL algorithm performed better with PCCT images compared to conventional CT images, achieving higher sensitivity for all occlusions and a marked improvement in identifying M2 occlusions, suggesting that improved image quality enhances detection capabilities but further research is necessary.
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Developing multifunctional nanomaterials is crucial to rising global concerns over environmental contamination caused by dye effluents and antibiotic resistance. This work presents cesium (Cs)-doped YO nanostructures (NSs) as viable options for catalytic dye degradation and antibacterial action. This study prepared yttrium oxide (YO) and various (2, 4, and 6 wt%) concentrations of Cs-doped YO NSs co-precipitation technique.

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Objectives: Brain tumor detection, classification and segmentation are challenging due to the heterogeneous nature of brain tumors. Different deep learning-based algorithms are available for object detection; however, the performance of detection algorithms on brain tumor data has not been widely explored. Therefore, we aim to compare different object detection algorithms (Faster R-CNN, YOLO & SSD) for brain tumor detection on MRI data.

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To evaluate the label accuracy and content of various hemp-derived cannabidiol (CBD) products (cannabinoid products with ≤0.3% Δ-tetrahydrocannabinol [THC]), as well as evaluate advertised claims on product labels. Hemp haircare, cosmetics, and food/drink products that were advertised to contain CBD were purchased from retail stores in the Baltimore, Maryland area (purchased in July 2020) and online (purchased in August 2020).

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Food and beverage products containing cannabidiol (CBD) is a growing industry, but some CBD products contain Δ-tetrahydrocannabinol (Δ-THC), despite being labeled as "THC-free". As CBD can convert to Δ-THC under acidic conditions, a potential cause is the formation of Δ-THC during storage of acidic CBD products. In this study, we investigated if acidic products (pH ≤ 4) fortified with CBD would facilitate conversion to THC over a 2-15-month time period.

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Background: Acute pulmonary embolism (APE) is a potentially life-threatening disorder, emphasizing the importance of accurate risk stratification and survival prognosis. The exploration of imaging biomarkers that can reflect patient survival holds the potential to further enhance the stratification of APE patients, enabling personalized treatment and early intervention. Therefore, in this study, we develop computed tomography pulmonary angiography (CTPA) radiomic signatures for the prognosis of 7- and 30-day all-cause mortality in patients with APE.

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Background Coronary artery calcium scoring (CACS) for coronary artery disease requires true noncontrast (TNC) CT alongside contrast-enhanced coronary CT angiography (CCTA). Photon-counting CT provides an algorithm (PureCalcium) for reconstructing virtual noncontrast images from CCTA specifically for CACS. Purpose To assess CACS differences based on PureCalcium images derived from contrast-enhanced photon-counting CCTA compared with TNC images and evaluate the impact of these differences on the clinically relevant classification of patients into plaque burden groups.

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Purpose: To determine the optimal virtual monoenergetic image (VMI) for detecting and assessing intracranial hemorrhage in unenhanced photon counting CT of the head based on the evaluation of quantitative and qualitative image quality parameters.

Methods: Sixty-three patients with acute intracranial hemorrhage and unenhanced CT of the head were retrospectively included. In these patients, 35 intraparenchymal, 39 intraventricular, 30 subarachnoidal, and 43 subdural hemorrhages were selected.

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Personalized treatment strategies based on non-invasive biomarkers have potential to improve patient management in patients with newly diagnosed glioblastoma (GBM). The residual tumour burden after surgery in GBM patients is a prognostic imaging biomarker. However, in clinical patient management, its assessment is a manual and time-consuming process that is at risk of inter-rater variability.

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Concerns about health hazards associated with the consumption of -delta-8-tetrahydrocannabinol products were highlighted in public health advisories from the U. S. Food and Drug Administration and U.

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Rationale And Objectives: Accurate and efficient estimation of patient height and weight is crucial to ensure patient safety and optimize the quality of magnetic resonance imaging (MRI) procedures. Several height and weight estimation methods have been proposed for use in adult patient management, but none is widely established. Estimation by the medical technologists for radiology (MTR) based on personal experience remains to be the most common method.

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Article Synopsis
  • Zn-Fe layered double hydroxide (LDH) was created using a low-temperature coprecipitation method, with varying concentrations of silver (Ag) and polyvinylpyrrolidone (PVP) added for enhanced properties.
  • The addition of Ag and PVP improved the material's bactericidal and catalytic activities by increasing oxygen vacancies and the number of active hydroxide adsorption sites.
  • The doped LDH effectively degraded rhodamine-B dye best in a basic environment and demonstrated strong antibacterial effects, revealing mechanisms behind its effectiveness through molecular docking studies involving specific bacterial enzymes.
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We have employed a co-precipitation method to synthesize different concentrations of carbon spheres (CSs) doped with cadmium sulfide (CdS) quantum dots (QDs) for catalytic reduction and antibacterial applications. Various morphological and structural characterization techniques were used to comprehensively analyze the CS effect on CdS QDs. The catalytic reduction efficiency of CS-doped CdS QDs was evaluated using rhodamine B dye.

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Introduction: Cannabidiol (CBD) has several potential benefits and therapeutic uses, especially in pain, inflammation, and anxiety. CBD has high hydrophobicity and very low solubility in water. CBD has also shown exceptionally low oral-gastrointestinal (oral-GI) bioavailability.

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The progressive trend of utilizing bioactive materials constitutes diverse materials exhibiting biocompatibility. The innovative aspect of this research is the tuning of the thermo-mechanical behavior of polyurethane (PU) composites with improved biocompatibility for vibrant applications. Polycaprolactone (CAPA) Mn = 2000 g-mol was used as a macrodiol, along with toluene diisocyanate (TDI) and hexamethylene diisocyanate (HMDI), to develop prepolymer chains, which were terminated with 1,4 butane diol (BD).

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Glioblastoma multiforme (GBM) is one of the most aggressive cancers with a low overall survival rate. The treatment of GBM is challenging due to the presence of the blood-brain barrier (BBB), which hinders drug delivery. Invasive procedures alone are not effective at completely removing such tumors.

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Article Synopsis
  • - The research aims to improve safe drinking water availability by developing new materials, specifically enhancing the properties of lanthanum oxide (LaO) through doping with yttrium (Y) and carbon spheres (Cs) to reduce charge carrier recombination and boost catalytic and antimicrobial activity.
  • - The study involved synthesizing different concentrations of Y and a constant amount of Cs using a coprecipitation technique, where Cs acts as a co-catalyst with its high surface area enhancing active sites and reducing recombination rates.
  • - Advanced techniques were used to analyze the structural and optical properties of the resulting nanostructures, and in silico molecular docking studies indicated that the Y/Cs-doped LaO nanostructures effectively inhibit
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Background: Sarcopenia is proposed as a novel imaging biomarker in several acute conditions regarding outcome and mortality. The aim of the present study was to investigate the prognostic role of the masseter muscles in patients with acute ischemic stroke (AIS).

Methods: Overall, 189 patients with AIS that received mechanical thrombectomy were retrospectively enrolled in this study.

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This study was used to evaluate the catalytic activity (CA) and bactericidal activity of α-MoO and Sm-g-CN-doped α-MoO composites prepared through an efficient, cost-effective coprecipitation route. Their characteristic studies verify the formation of α-MoO and its composites (3, 6, and 9 mL Sm-g-CN-doped α-MoO), which showed high crystallinity, as confirmed by X-ray diffraction (XRD) analysis. The production of superoxide and hydroxyl radicals due to charge transfer through α-MoO and g-CN eventually forms electrons in g-CN and holes around α-MoO.

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Curcumin (diferuloylmethane), the primary curcuminoid in turmeric rhizome, has been acknowledged as a bioactive compound for numerous pharmacological activities. Nonetheless, the hydrophobic nature, rapid metabolism, and physicochemical and biological instability of this phenolic compound correspond to its poor bioavailability. So, recent scientific advances have found many components and strategies for enhancing the bioavailability of curcumin with the inclusion of biotechnology and nanotechnology to address its existing limitations.

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Cationic dyes present in industrial effluents significantly reduce the effectiveness of remediation operations. Considering the terrible impact of these pollutants on environment and biodiversity, investigating strategies to remove potentially harmful compounds from water is becoming an increasingly intriguing issue. In this work, we employed a simple hydrothermal technique to synthesize Fe-doped CdO (2, 4, and 6 wt %) nanostructures and assessed their efficacy in degrading methylene blue (MB) dye and inhibiting the growth of and , respectively.

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Aim: This study aims to design and evaluate zeta potential shifting nanoemulsions comprising single and gemini type tyrosine-based surfactants for specific cleavage by tyrosine phosphatase.

Methods: Tyrosine-based surfactants, either single 4-(2-amino-3-(dodecylamino)-3-oxopropyl)phenyl dihydrogen phosphate (AF1) or gemini 4-(2-amino-3-((1-(dodecylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-3-oxopropyl)phenyl dihydrogen phosphate (AF2) type were synthesized via amide bond formation of tyrosine with dodecylamine followed by phosphorylation. These surfactants were incorporated into nanoemulsions.

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This work demonstrates the degradation of toxic RhB (rhodamine B) dye from polluted water in various pH environments. It assesses the antibacterial action of CDs (carbon dots)/CS (chitosan)-doped LaO (lanthanum oxide) NRs (nanorods). CS and CDs have been introduced as dopants to modify the characteristics of LaO to achieve efficient outcomes.

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In this study, MoO nanostructures were prepared, doped with various concentrations of graphene oxide (2 and 4% GO) and a fixed amount of polyvinylpyrrolidone (PVP) using the co-precipitation method. The motive of this study was to examine the catalytic and antimicrobial efficacy with evidential molecular docking analyses of GO/PVP-doped MoO. GO and PVP were utilized as doping agents to reduce the exciton recombination rate of MoO by providing more active sites that increase the antibacterial activity of MoO.

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