Publications by authors named "Iram Asrar"
Article Synopsis
- Endometrial cancer is a significant health issue for women worldwide, being the sixth most common cancer and the 14th leading cause of cancer-related deaths, particularly for high-grade tumors like UEC, DEC, and CS.
- The study analyzed data from 71 patients diagnosed with these aggressive tumors at SKMCH&RC from 2011 to 2022, focusing on clinicopathological characteristics and survival rates using statistical tools like SPSS and Kaplan-Meier analysis.
- Results indicated that tumors showed significant correlations with factors such as myometrial invasion and lympho-vascular invasion, with a notable 5-year overall survival rate of 59.1% for those diagnosed at an early pathological stage.
Background: The updated version of predictive classification for immunoglobulin A nephropathy (IgAN) prognosis "The Oxford Classification" identifies five histopathological features including mesangial hypercellularity (M), endocapillary proliferation (E), segmental glomerulosclerosis (S), tubular atrophy/interstitial fibrosis (T) and crescents (C), the MEST-C. However, few studies suggest that tubulointerstitial inflammation, which is not included in the MEST-C, is also linked to disease progression and is, consequently, a neglected determinant of prognosis among others. Therefore, there is a need to evaluate this histopathological parameter in patients with IgA nephropathy.
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