The Association of Demodex with Chalazia: A Histopathologic Study of the Eyelid.

Purpose: To investigate the association of Demodex with chalazia and to describe the associated histopathologic changes in the eyelid tissue.

Methods: In a retrospective histopathologic case-control study, 78 ectropion/entropion repair eyelid wedge resections were examined. Serial sections were obtained on formalin-fixed, paraffin-embedded tissues, stained with hematoxylin-eosin and studied by light microscopy.

Recurrence of Ocular Surface Squamous Neoplasia Treated With Excisional Biopsy and Cryotherapy.

Purpose: To evaluate the recurrence rate of ocular surface squamous neoplasias (OSSN) after excision and cryotherapy in an academic cornea practice and to determine factors associated with recurrence.

Design: Retrospective interventional case series.

Methods: All cases of OSSN from 1998 through 2013 that were treated with excisional biopsy and adjunctive cryotherapy were retrospectively reviewed.

Descemet stripping endothelial keratoplasty for the treatment of combined fuchs corneal endothelial dystrophy and keratoconus.

Purpose: To report the first case series of patients with Fuchs corneal endothelial dystrophy (FCD) and keratoconus (KCN) who underwent Descemet stripping endothelial keratoplasty (DSEK).

Methods: This is a retrospective case series of 6 eyes of 4 patients with combined FCD and KCN who underwent DSEK at 3 different centers. Clinical information collected included corneal topography measurements, central corneal thickness, and endothelial cell count.

Immunologic graft rejection in descemet's stripping endothelial keratoplasty and penetrating keratoplasty for endothelial disease.

Objective: To evaluate and compare the cumulative incidence and risk factors for first-episode immunologic graft rejection in Descemet's stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK) and to identify potential risk factors for rejection.

Design: Retrospective chart review.

Participants: All patients who underwent PK or DSAEK for endothelial disease at the Department of Ophthalmology, North Shore LIJ, between January 2004 and June 2010.

Textural interface opacity after descemet stripping automated endothelial keratoplasty: a report of 30 cases and possible etiology.

Purpose: Descemet stripping automated endothelial keratoplasty (DSAEK) has its own set of complications including interface abnormalities. This case series presents the largest number of patients who developed textural interface opacity (TIO) at the graft-host interface after DSAEK.

Methods: This is a retrospective multicenter case series of 30 patients from 7 institutions with the finding of TIO.

Full-thickness corneal "vent incisions": how deep does the epithelium penetrate?

Purpose: To evaluate epithelial cell penetration produced by full-thickness "vent incisions."

Methods: Six donor human corneas with intact epithelium were placed on an artificial anterior chamber. Four perforating paracentral vent incisions were made in each cornea using a diamond knife.

Spontaneous reattachment of Descemet stripping automated endothelial keratoplasty lenticles: a case series of 12 patients.

Purpose: To review 12 cases of postoperative detachment and spontaneous reattachment of Descemet stripping automated endothelial keratoplasty (DSAEK) lenticles.

Design: Retrospective, observational case series.

Methods: This was a review of patients undergoing DSAEK at 7 institutions.

Preservative-free low-dose dexamethasone for the treatment of chronic ocular surface disease refractory to standard therapy.

Purpose: To evaluate the short-term safety and efficacy of topical preservative-free dexamethasone 0.01% for the treatment of ocular surface disease and/or tearing refractory to conventional treatments.

Methods: Retrospective chart review of all patients who received topical unpreserved dexamethasone 0.

Safety of overnight orthokeratology for myopia: a report by the American Academy of Ophthalmology.

Objective: To review the published literature to evaluate the safety of overnight orthokeratology (OOK) for the treatment of myopia.

Methods: Repeated searches of peer-reviewed literature were conducted in PubMed (limited to the English language) and the Cochrane Central Register of Controlled Trials (no language limitations) for 2005, 2006, and 2007. The searches yielded 495 citations.

Visual outcome and bacterial sensitivity after methicillin-resistant Staphylococcus aureus-associated acute endophthalmitis.

Purpose: To determine the frequency, visual outcome, and bacterial sensitivity in cases of methicillin-resistant Staphylococcus aureus (MRSA)-associated acute postoperative endophthalmitis occurring after cataract surgery.

Design: Retrospective, consecutive, observational case series.

Methods: Sixty-four cases of acute endophthalmitis occurring within six weeks after cataract surgery were identified over a three-year interval at a single vitreoretinal practice.

In vitro activity of fluoroquinolones, vancomycin, and gentamicin against methicillin-resistant Staphylococcus aureus ocular isolates.

Purpose: To determine the antibacterial activity of fluoroquinolones, vancomycin, and gentamicin against methicillin-resistant Staphylococcus aureus (MRSA) ocular surface isolates.

Design: Retrospective review.

Methods: MRSA isolates were obtained from 21 patients.

Acute endophthalmitis in eyes treated prophylactically with gatifloxacin and moxifloxacin.

Purpose: To study the use of prophylactic fourth-generation fluoroquinolone antibiotics, gatifloxacin and moxifloxacin, and bacterial sensitivity in cases of acute postoperative endophthalmitis following cataract surgery.

Design: Retrospective, consecutive, observational case series.

Methods: Forty-two eyes of 42 patients with acute endophthalmitis occurring within six weeks after cataract surgery were identified.

Dacryocystitis caused by community-onset methicillin-resistant Staphylococcus aureus.

Purpose: To describe the occurrence of community-onset methicillin-resistant Staphylococcus aureus (MRSA) infections of the lacrimal system and their treatment.

Methods: This cases series consisted of data obtained from seven clinical cases of acute or subacute MRSA dacryocystitis, with or without concurrent conjunctivitis, occurring in nonhospitalized individuals presenting between December 2001 and July 2003. Clinical presentations, microbial culture results, treatment modalities, and outcomes were retrospectively reviewed.

A comparison of the clinical efficacy of pheniramine maleate/naphazoline hydrochloride ophthalmic solution and olopatadine hydrochloride ophthalmic solution in the conjunctival allergen challenge model.

Background: The signs and symptoms of allergic conjunctivitis include ocular redness and itching. Two treatment options currently indicated for acute ocular allergic reaction are pheniramine maleate 0.3%/naphazoline hydrochloride 0.

Confocal microscopy: a report by the American Academy of Ophthalmology.

Objective: To review the available evidence for the use of confocal microscopy in diagnosing infectious keratitis and for other applications for ophthalmic practice.

Methods: A MEDLINE search of the peer-reviewed literature for the years 1990 to 2001 yielded 94 citations. The search was limited to studies of human subjects published in English with abstracts.

Ketotifen fumarate treatment of superior limbic keratoconjunctivitis.

Purpose: To report the effect of topically applied ketotifen fumarate in the treatment of superior limbic keratoconjunctivitis (SLK).

Methods: Five patients with clinical findings of bilateral SLK with no relief of symptoms with standard reported modalities of treatment were treated with topical ketotifen fumarate twice daily in both eyes. All patients were evaluated 2 to 4 weeks after initiation of treatment of symptomatic and clinical improvement and at regular intervals thereafter.