Adverse financial and clinical burden of the use of prophylactic antibiotics in neurosurgical patients.

Background: Current guidance does not support the administration of prophylactic antibiotics in non-infected post-operative surgical cases including neurosurgery.

Materials And Methods: This paper is a qualitative assessment, highlighting the economic cost of excessive antimicrobial prescription and the healthcare costs of the extra days of admission in hospital.

Results: One hundred and one neurosurgical cases were analysed in a single institution over a one-year period.

Intratumoral and Peritumoral Brain Abscess Concomitant with Glioblastoma: Report of Two Cases with Review of Literature.

Intracranial abscess coexistent with a high grade glioma, without prior surgical intervention, is an unusual occurrence. This paper presents two such cases with abscess surrounding the glioblastoma in an immunocompromised individual and abscess within the glioblastoma in an immunocompetent patient. Adjuvant therapy was tapered as per each patient's clinical response.