Background: To investigate the association of optic neuritis (ON) after the COVID-19 vaccines.
Methods: Cases of ON from Vaccine Adverse Event Reporting System (VAERS) were collected and divided into the prepandemic, COVID-19 pandemic, and COVID-19 vaccine periods. Reporting rates were calculated based on estimates of vaccines administered.
Currently, we reported the synthesis of six novel salicylaldehyde-based thiosemicarbazones () via condensation of salicylaldehyde with respective thiosemicarbazide. Through various spectroscopic methods, UV-visible and NMR, the chemical structures of compounds were determined. Along with synthesis, a computational study was also performed at the M06/6-31G(d,p) functional.
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