A Novel Presentation of Metaphyseal Chondrodysplasia, Schmid Type with Factor VII Deficiency.

Metaphyseal chondrodysplasia, Schmid type (MDSC) is a rare inherited autosomal disorder with characteristic skeletal deformities striking on radiological imaging, which includes metaphyseal cupping and fraying. Physical examination reveals short stature in early childhood, frontoparietal bossing, rachitic rosary, genu varum and valgum, and coxa vara usually. We believe that the constellation of clinical and radiographic findings of MDSC might look similar to vitamin D resistant rickets; hence, genetic analysis is needed to overcome diagnostic challenges faced by physicians to avoid unnecessary vitamin D supplementation in individuals.

A Fatal Case of Primary Orbital Ewing's Sarcoma with Intracranial Extensions in a Six-year-old Girl.

Ewing's sarcoma (ES) is the second most common skeletal tumor seen in children and adolescents which typically involves the long bones and the axial skeleton. ES involving the orbits is extremely rare and can lead to serious consequences. Patients usually present with fever, localized bone pain which increases during the night time, and a visible mass, often with a preceding history of trauma.

Isolated corrosive pyloric stenosis without oesophageal involvement: an experience of 21 years.

Background And Study Aims: Corrosive ingestion is common in Asia and it is a frequent cause of morbidity secondary to intense fibrotic reaction and stricture formation of the oesophagus. Isolated corrosive pyloric stenosis without oesophageal involvement is an uncommon phenomenon.

Patients And Methods: All consecutive patients, with corrosive ingestion in the last two decades, were reviewed and analysed.