Berberine protects against metformin-associated lactic acidosis in induced diabetes mellitus.

Objectives: Causality of occurrence of metformin-associated lactic acidosis (MALA) is a clinical problem. Currently, there is no drug available to prevent MALA. The present study was conducted to evaluate the protective effect of Berberine (BBR) against MALA in induced diabetic rat model.

Serum zinc and magnesium in type-2 diabetic patients.

Objective: To assess serum zinc and magnesium level in type-2 diabetic patients and the effect of age, gender, glycemic control and duration of diabetes on these trace elements in comparison with those of control subjects.

Study Design: Non-interventional case control study.

Place And Duration Of Study: Department of Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad, from October 2007 to March 2008.

Intestinal amoebiasis in children and its effect on nutritional status.

Objective: To determine the frequency and clinical presentation of amoebic diarrhea in children and its effect on the nutritional status of the affected children.

Study Design: Descriptive.

Place And Duration Of Study: Department of Diarrhea Treatment Unit (DTU), Dow Medical College and Civil Hospital, Karachi, from November 1998 to April 2001.