Publications by authors named "Ionnis Mantzaris"
J Hematol Oncol
July 2013
Article Synopsis
- - Myelodysplastic syndromes (MDS) are blood disorders leading to low blood counts and can evolve into leukemia; however, the primary issues for patients usually stem from chronic low counts rather than the transformation.
- - Traditional treatments for MDS have mixed results and significant side effects, particularly for older patients, which creates a need for targeted therapies that can improve blood counts and address bone marrow failure.
- - Various targeted strategies are being researched, including inhibitors for specific signaling pathways (like p38 MAPK and TGF-β), which have shown promising results in clinical trials, highlighting the potential for more effective treatments for MDS.
