Publications by authors named "Ion Dragalin"
Article Synopsis
- Researchers synthesized a series of fourteen compounds based on homodrimane carboxylic acids and tested their effectiveness against five fungi species and two bacteria strains.
- The synthesis process included several chemical reactions, such as decarboxylative cyclization and condensation, leading to unexpected products whose structures and formation mechanisms were analyzed.
- Some synthesized compounds demonstrated significantly higher antifungal and antibacterial activity than established standards, with specific compounds showing selective antifungal properties at low concentrations.
The producers of essential oils from the Republic of Moldova care about the quality of their products and at the same time, try to capitalize on the waste from processing. The purpose of the present study was to analyze the chemical composition of lavender ( L.) essential oil and some by-products derived from its production (residual water, residual herbs), as well as to assess their "in vitro" antimicrobial activity.
View Article and Find Full Text PDFUsing sclareol and sclareolide as starting materials, the guanidine derivatives of 12-amino-11-dihomodrimane-8α-ol and 13-amino-14,15-bis-dinorlabd-8(9)-ene were synthesized by the reaction of the corresponding amines with sodium hydrogencyanamide in ethanol - water solution. Monoacyl- and diacylguanidines were prepared from activated with N,N-carbonyldiimidazole Δ-bicyclohomofarnesenoic acid by the reaction with guanidine. Their structures were confirmed by the H and C NMR, IR spectral and elemental analysis data.
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