J Med Microbiol
February 2023
Healthcare-associated infections (HAIs) are the most recurrent adverse event in hospitals worldwide and represent an important public health problem. There are a paucity of multicentric data describing severe HAIs such as bloodstream infection (BSI) and pneumonia in Brazil. To provide an up-to-date picture of the extent and patterns of HAIs in adult intensive care units (ICUs), as well as to identify variables associated with the risk of development of severe infections.
View Article and Find Full Text PDFAm J Cardiovasc Dis
April 2021
Background: Infections are surgical severe adverse events that pose risks to patient safety in health services, in addition to increasing costs and morbidity and mortality.
Aim: This study aims to describe the infectious profile of patients undergoing cardiac surgery and associate comorbidities and lifestyle habits with surgical wound infection.
Design: Observational and retrospective study.
This study used whole-genome sequencing to analyze the first case of NDM-1-producing belonging to the novel sequence type 1465/CC216 recovered in Brazil. The study identified an unusual plasmid carrying gene, in which some genes of the Tn transposon were lost. Besides, on the chromosome, the strain reported here presented gene, a variant of gene, and with IS upstream.
View Article and Find Full Text PDFThe purpose of this study was to identify the risk factors that predispose patients who are hospitalized with pressure ulcers (PUs) colonized by Gram-negative bacilli (GNB) to develop bacteremia. In addition, we also detected main phenotypes of resistance in infected and uninfected PUs. A prospective cohort study was conducted at the Clinical Hospital of the Federal University of Uberlândia including patients with Stage II or greater PUs, colonized or not with GNB, from August 2009 to July 2010.
View Article and Find Full Text PDFUnlabelled: Pressure ulcers (PU) are a major reservoir of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals. The objectives of this study were to estimate the prevalence of MRSA colonization in PU of hospitalized patients with Stage II or higher PU, to identify risk factors for colonization of these wounds, and to ascertain whether MRSA colonization of PU increases the risk of MRSA bacteremia.
Methods: This study was conducted at the Clinical Hospital of Federal University of Uberlandia, MG, Brazil.