Publications by authors named "Iok Tong Chong"
Purpose: To evaluate the efficacy of a novel contact lens sensor system (CLS) in detecting continuous intraocular pressure (IOP) variations following positional transitions, and to explore these IOP variation patterns among normal subjects, untreated glaucoma patients, and untreated ocular hypertension (OHT) subjects.
Methods: This prospective comparative study included 20 normal subjects, 14 high tension glaucoma (HTG) patients, 16 normal tension glaucoma (NTG) patients, and 14 OHT subjects. Participants wore the CLS for continuous IOP monitoring while undergoing sequential body position changes: from sitting to supine to a 10° head-down tilt (HDT), with each position maintained for ten minutes.
Purpose: To investigate the relationship between intraocular pressure (IOP) changes and corneal biomechanical properties, determine the quantitative relationship between IOP changes and corneal biomechanical properties in patients with glaucoma and observe the differences among different types of glaucoma when the effects of high-level IOP were excluded.
Design: Prospective clinical cohort study.
Methods: Setting: Institutional.
Aims: To investigate the physiological nyctohemeral intraocular pressure (IOP) rhythms of normal Chinese adults using a novel contact lens sensor system (CLS) that can output IOP in millimetres of mercury (mm Hg) continuously.
Methods: Fifty-nine eyes of 59 normal Chinese adults completed 24-hour IOP monitoring using the novel CLS. A descriptive analysis was conducted on the 24-hour IOP mean, peak and acrophase, trough and bathyphase, fluctuation, and mean amplitude of intraocular pressure excursion (MAPE).
Article Synopsis
- The study evaluated the safety and tolerability of a new contact lens sensor (CLS) designed for continuous monitoring of intraocular pressure (IOP) in human eyes over 3 and 24 hours.
- Results indicated increases in corneal fluorescein staining and discomfort after IOP monitoring, but most measures, including best-corrected visual acuity and tear break-up time, returned to baseline after one day.
- Overall, the CLS demonstrated promising safety and tolerability for 24-hour IOP monitoring without significant differences between normal subjects and glaucoma patients.
Purpose: To assess and compare the corneal biomechanics of normal-tension glaucoma (NTG), high-tension glaucoma (HTG), and normal controls based on stiffness and modulus. The correlations among central corneal thickness (CCT), visual field, retinal nerve fiber layer (RNFL) thickness, and corneal biomechanics in glaucoma eyes were also evaluated.
Design: A prospective, cross-sectional, comparative study.
Purpose: To evaluate the ability of the new in vivo corneal indentation device (CID) to measure corneal biomechanical properties.
Methods And Results: In total, 186 eyes from 46 healthy subjects, 107 patients with primary open-angle glaucoma, and 33 patients with ocular hypertension were enrolled in a cross-sectional study. Measurements were performed using corneal visualization Scheimpflug technology (Corvis ST) and the CID.