Publications by authors named "Ioannis Nikolopoulos"

Predictive tools provide a unique opportunity to explain the observed differences in outcome between patients of the COVID-19 pandemic. The aim of this study was to associate individual demographic and clinical characteristics with disease severity in COVID-19 patients and to highlight the importance of machine learning (ML) in disease prognosis. The study enrolled 344 unvaccinated patients with confirmed SARS-CoV-2 infection.

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Two nickel alumina catalysts containing 60 wt. % Ni were synthesized by wet impregnation and co-precipitation in order to study the effect of preparation methods on the catalytic efficiency concerning the transformation of sunflower oil into green diesel. The effect of activation temperature on the catalytic efficiency of the most active catalyst was also studied.

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  • The ChoCO-W study aimed to examine the effects of COVID-19 on the clinical presentation and outcomes of acute cholecystitis, particularly focusing on the rise of gangrenous cases during the pandemic.
  • Over 2,800 patients from 42 countries were enrolled, with a notable 6.9% testing positive for COVID-19, revealing a significantly higher prevalence of preexisting conditions and more severe outcomes in this group compared to those without the virus.
  • Patients with COVID-19 experienced higher postoperative complications (32.2% vs. 11.7%), longer hospital stays (13.21 days vs. 6.51 days), increased mortality rates (13.4% vs. 1.7
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Background: Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. The objectives of this study were to identify clinical and laboratory predictors for in-hospital mortality in patients with acute peritonitis and to develop a warning score system, based on easily recognizable and assessable variables, globally accepted.

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The performances of porous materials are closely related to the accessibility and interconnectivity of their porous domains. Visualizing pore architecture and its role on functionality-for example, mass transport-has been a challenge so far, and traditional bulk and often non-visual pore measurements have to suffice in most cases. Here, we present an integrated, facile fluorescence microscopy approach to visualize the pore accessibility and interconnectivity of industrial-grade catalyst bodies, and link it unequivocally with their catalytic performance.

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Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis.

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Extra-abdominal complications of pancreatitis such as pancreaticopleural fistulae are rare. A pancreaticopleural fistula occurs when inflammation of the pancreas and pancreatic ductal disruption lead to leakage of secretions through a fistulous tract into the thorax. The underlying aetiology in the majority of cases is alcohol-induced chronic pancreatitis.

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  • Scientists created a new score to check how serious infections in the tummy area are for patients.
  • They studied over 4,500 patients in many hospitals around the world to see what factors affect survival rates.
  • The new score is very accurate in predicting if a patient will survive or not, which can help doctors make better decisions.
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  • This study examines the impact of 3-month continuous positive airway pressure (CPAP) therapy on various health measures in patients with obstructive sleep apnea syndrome (OSAS), focusing on important factors like endothelial function and inflammation.
  • Results indicate that CPAP significantly improved endothelial-dependent dilation and reduced blood pressure and inflammatory markers in patients, suggesting beneficial effects of CPAP on cardiovascular health.
  • The research included 40 patients (24 males and 16 females) with OSAS, and while improvements were noted for both genders, only male patients demonstrated similar results in certain metrics.
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Computed tomography (CT) imaging is the most appropriate diagnostic tool to confirm suspected left colonic diverticulitis. However, the utility of CT imaging goes beyond accurate diagnosis of diverticulitis; the grade of severity on CT imaging may drive treatment planning of patients presenting with acute diverticulitis. The appropriate management of left colon acute diverticulitis remains still debated because of the vast spectrum of clinical presentations and different approaches to treatment proposed.

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Meckel's diverticulum is the commonest congenital anomaly of the small intestine. It can, however, present acutely relating to a number of complications that may require emergency surgery and possible bowel resection. Perforation is a rare complication and there are only seven cases reported of an inflamed Meckel's diverticulum due to a chicken bone.

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Purposes: The objective of this study was to test the efficacy of an equine pericardial patch for repairing full-thickness defects of the stomach wall.

Methods: Circular defects, 1.5 cm in diameter, were created on the anterior wall of the stomach of 12 female New Zealand rabbits.

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Introduction. Femoral hernias are at high risk of strangulation due to the narrow femoral canal and femoral ring. This can lead to symptoms of obstruction or strangulation requiring emergency surgery and possible bowel resection.

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Introduction: Obstructive sleep apnea (OSA) is a highly prevalent condition related to several cardiovascular complications. We assessed the effects of continuous positive airway pressure (CPAP) treatment on myocardial performance and various somatometric parameters in patients with severe OSA receiving CPAP.

Materials And Methods: This is a prospective longitudinal study of 44 patients aged 55.

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Vaginal evisceration is a rare condition most commonly associated with previous vaginal surgery. It usually presents with vaginal bleeding, lower abdominal pain and a protruding mass, and requires immediate assessment and surgical management to salvage the prolapsed bowel. Any delay in the treatment may result in bowel ischaemia and perforation which is associated with higher morbidity and mortality.

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Torsion of the gallbladder resulting in a volvulus is a rare clinical finding that poses a diagnostic challenge preoperatively to both surgeons and radiologists. It is thought to occur secondary to a redundant mesentery where rotation of the gallbladder occurs along the axis of the cystic duct and cystic artery. Gallbladder volvulus commonly presents as acute cholecystitis and is rarely diagnosed preoperatively.

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Background: Continuous positive airway pressure (CPAP) is the most effective method for treating obstructive sleep apnea syndrome (OSAS) and alleviating symptoms. Improved sleep quality with effective CPAP therapy might also contribute to attenuated systemic inflammation and improved endothelial function, with subsequent reduction of cardiovascular risk. The aim of this study was to assess the effect of 3-month CPAP therapy on brachial artery flow-mediated dilation (FMD) and plasma C-reactive protein (CRP) levels in patients with OSAS.

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Article Synopsis
  • Large ganglionic cysts from the infrapatellar fat pad are rare, requiring surgical excision for treatment.
  • A case study details a 37-year-old man with knee pain due to a large cyst, identified through MRI, which lacked any extension into the joint.
  • Although these cysts are typically asymptomatic, they are often confused with other knee injuries; large cases necessitate open surgery rather than minimally invasive methods.
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