Severe toxic effect of methylene blue 1% on iris epithelium and corneal endothelium.

Purpose: To report a case of corneal endothelial decompensation and iris pigment dispersion following the inadvertent use of methylene blue 1% for capsular staining during cataract surgery.

Design: Case report.

Methods: During an otherwise routine phacoemulsification cataract surgery, inadvertent anterior capsule staining with methylene blue 1% instead of trypan blue 0.