Calcaneal melanoma; our rare case and review of the literature.

Melanoma is a serious disease with an increasing incidence and mortality of great extent. A case of cutaneous calcaneal melanoma is described with the whole management we followed. After injection of 99 m Tc-nanocoll for sentinel lymph node detection and its localization at the left inguinal region, its excision performed with the help of gamma probe.

Correlation between Ki67 and breast cancer prognosis.

Background: Ki67 is an immunohistochemical proliferation marker in many types of cancer and has been widely studied among breast cancer patients mostly through retrospective studies.

Methods: The MEDLINE/PubMed database was searched for publications with the medical subject heading 'Ki 67' and the key words 'breast', 'cancer', and 'prognosis'. We restricted our search to articles published until 2012.

Gastrocolic fistulae; From Haller till nowadays.

Gastrocolic Fistula is, in the majority of cases the pathological communication between stomach and transverse colon, because cases involved with the small intestine, pancreas and skin have been also documented, even though are rare. It occurs mostly in adults, but they can be present to infants, as well, as a result of congenital abnormalities or iatrogenic procedures (i.e.

Cell cyclins: triggering elements of cancer or not?

Cyclins are indispensable elements of the cell cycle and derangement of their function can lead to cancer formation. Recent studies have also revealed more mechanisms through which cyclins can express their oncogenic potential. This review focuses on the aberrant expression of G1/S cyclins and especially cyclin D and cyclin E; the pathways through which they lead to tumour formation and their involvement in different types of cancer.