Validity of intraoperative gross examination of myometrial invasion in patients with endometrial cancer: a meta-analysis.

Objective: The current recommended endometrial cancer surgical treatment is abdominal extrafascial total hysterectomy with bilateral salpingo-oophorectomy followed by pelvic lymphadenectomy if >50% myometrial invasion is estimated by intraoperative gross examination (IGE). This meta-analysis aims to quantify evidence regarding the validity/predictive value of IGE staging compared with final histology.

Design: Meta-analysis of studies published until October 2011.