Publications by Ioannis Charitakis

Publications by authors named "Ioannis Charitakis"

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Kv1.3 Channel Up-Regulation in Peripheral Blood T Lymphocytes of Patients With Multiple Sclerosis.

Ioannis Markakis Ioannis Charitakis Christine Beeton Melpomeni Galani Elpida Repousi

Front Pharmacol

September 2021

Voltage-gated Kv1.3 potassium channels are key regulators of T lymphocyte activation, proliferation and cytokine production, by providing the necessary membrane hyper-polarization for calcium influx following immune stimulation. It is noteworthy that an accumulating body of and evidence links these channels to multiple sclerosis pathophysiology.

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