Publications by authors named "Ioanna Giotaki"
Background: In the 19th century, neurosyphilis was the most frequent cause of dementia in Western Europe. Now dementia caused by syphilis has become rare in Germany. We studied whether routine testing of patients with cognitive abnormalities or neuropathy for antibodies against Treponema pallidum has therapeutic consequences in geriatric patients.
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- * His cerebrospinal fluid (CSF) analysis indicated similarities to tuberculous meningitis, despite the lengthy delay in treatment; he received voriconazole and fluconazole, which led to recovery with mild lingering effects.
- * This case highlights that chronic meningitis can occur even in patients with normal immune function, that delayed diagnosis can still allow for positive outcomes, and that voriconazole may be effective as a standalone treatment for this condition.
Background: The detection of cerebrospinal fluid (CSF)-specific oligoclonal bands (OCB) as well as an elevated antibody production directed against neurotrophic viruses remain hallmark findings in multiple sclerosis (MS). In general, individual patients show a unique pattern of OCB, which is believed to persist over time. Here, the authors revisited this assumption and investigated to what extent common anti-inflammatory MS medications can alter the level of immunoglobulins produced within the CSF.
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