Publications by authors named "Ioanna Efstathiou"
Article Synopsis
- Resistance in dermatophytes to antifungal treatments is becoming a major global health concern, prompting the research team to create an agar-based screening method for specific antifungal drugs.
- The study involved 40 dermatophyte isolates to validate the screening method's effectiveness in identifying susceptibility to terbinafine, itraconazole, and amorolfine, focusing on various mutations in the squalene epoxidase gene.
- The optimal testing conditions were established, showing that the method can reliably detect drug-resistant strains and has the potential for use in routine diagnostic labs.
Objectives: Current reference susceptibility testing methods of Aspergillus require visual reading, which is subjective and necessitates experienced staff. We compared spectrophotometric and visual MIC reading of EUCAST E.Def 9.
View Article and Find Full Text PDFisolates with reduced susceptibility to antifungals are now increasingly reported worldwide. We therefore studied the molecular epidemiology and the in vitro antifungal susceptibility patterns of Greek isolates over the last 10 years with the newly released EUCAST reference method for dermatophytes. Literature was reviewed to assess the global burden of antifungal resistance in spp.
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