Publications by authors named "Ioanna A Comstock"

Anticancer agents can impair ovarian function, resulting in premature menopause and associated long-term health effects. Ovarian toxicity is not usually adequately assessed in trials of anticancer agents, leaving an important information gap for patients facing therapy choices. This American Society of Clinical Oncology (ASCO) statement provides information about the incorporation of ovarian toxicity measures in trial design.

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Article Synopsis
  • The study looked at how useful and acceptable home pregnancy tests (MLPTs) are for women after they received help to get pregnant.
  • 104 women from two different clinics took part and used MLPTs alongside regular doctor tests for six weeks.
  • Results showed that most women found the MLPTs easy to use and liked using them, and the test results matched well with the doctors' tests.
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Objective: To analyze the transcriptomic profile of endometrial gene alterations during the window of implantation in infertile obese patients.

Design: Multicenter, prospective, case-control study.

Setting: Three academic medical centers for reproductive medicine.

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Article Synopsis
  • - The study examines how a woman's Body Mass Index (BMI) and metabolic health affect the rate of blastocyst formation during IVF treatments.
  • - Researchers analyzed data from patients of various weight categories, concluding that normal-weight women had a significantly higher blastocyst formation rate compared to those who were overweight or obese.
  • - The findings suggest that the metabolic environment in overweight and obese women negatively impacts embryo quality, potentially leading to lower reproductive success rates.
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Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval. The patient was admitted to the intensive care unit for resuscitation with blood products.

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