Adenosine involvement on bronchial reactivity modulation by diesel exhaust.

Unlabelled: In recent decades, epidemiologic investigations have suggested a strong relationship between air pollution and an increase in the prevalence of allergic rhinitis and asthma.

Aim: To investigate the possible involvement of adenosine (AD) in bronchomotor effects of diesel exhaust (DE).

Material And Method: Isolated bronchi from ovalbumin (OVA) sensitized rats were challenged in presence or absence of diesel exhaust extract (DEE).