Establishment of a continuous culture of in human erythrocytes reveals unusually high tolerance to recommended therapies.

Human babesiosis is an emerging tick-borne disease caused by apicomplexan parasites of the genus Clinical cases caused by have been associated with high parasite burden, severe pathology, and death. In both mice and hamsters, the parasite causes uncontrolled fulminant infections, which ultimately lead to death. Resolving these infections requires knowledge of biology, virulence, and susceptibility to anti-infectives, but little is known and further research is hindered by a lack of relevant model systems.