Publications by authors named "Ioana Balinisteanu"
Acromegaly is a rare endocrine disorder characterized by the excessive production of growth hormone (GH) in adulthood. Currently, it is understood that certain pituitary neuroendocrine tumors (PitNETs) exhibit a hereditary predisposition. These tumors' genetic patterns fall into two categories: isolated and syndromic tumors.
View Article and Find Full Text PDFArticle Synopsis
- Cancer predisposition syndromes are mainly caused by inherited genetic mutations, often passed down in an autosomal dominant manner, leading to varied cancer risks throughout life and affecting multiple organs, including the thyroid.
- Understanding the diverse clinical presentations and genetic connections in thyroid cancers related to these syndromes is crucial for proper early treatment of patients and their families.
- This review compiles the latest information on the genes and proteins associated with thyroid cancer predisposition syndromes and explores the complexities of differences in mutation types and clinical outcomes.