The α-glucosidase inhibitory activity of avicularin and 4-O-methyl gallic acid isolated from leaves.

Diabetes Mellitus is the main cause of death on a global scale. In 2019, there were 463 million people with diabetes, and WHO predicts that by 2030, there will be 578 million. As an antidiabetic agent, α-glucosidase inhibitors are one of the methods employed to reduce the prevalence of diabetes.

UHPLC-Q-Orbitrap HR-MS-Based Metabolomics for Profiling the Sida rhombifolia Metabolites with Different Plant Organs and Cultivation Ages.

Plant organs and cultivation ages can result in different compositions and concentration levels of plant metabolites. The metabolite profile of plants can be determined using liquid chromatography. This study determined the metabolite profiles of leaves, stems, and roots of Sida rhombifolia at different cultivation ages at 3, 4, and 5 months post-planting (MPP) using liquid chromatography-mass spectrometry/mass spectrometry (LC/MS/MS).

Improvement in Pharmacological Activity of Mahkota Dewa (Phaleria macrocarpa (Schef. Boerl)) Seed Extracts in Nanoemulsion Dosage Form: In Vitro and In Vivo Studies.

Background: Mahkota Dewa (Phaleria macrocarpa) seed has various phytochemical compounds and low pharmacological activities, including antioxidant and anti-inflammatory activities.

Objective: This research aimed to study nanoemulsion preparations of Mahkota Dewa seed (NE-BMD) for their anti-oxidant and anti-inflammatory properties.

Method: The nanoemulsion was prepared using an ultrasonication probe and followed by selecting two formulations, F7 and F8.

Potential Antioxidative Activity of Waste Product of Purple Sweet Potato ( Lam.).

<b>Background and Objective:</b> Antioxidants are substances that can deactivate free radicals. Phenol and flavonoid are antioxidant compounds widely found in plants, including purple sweet potato (<i>Ipomoea batatas</i> L.).

extracts stimulates bone healing in alveolar socket following tooth extraction.

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In Vitro Alpha-Glucosidase Inhibitory Activity and the Isolation of Luteolin from the Flower of (Delile) Sch. Bip ex Walp.

Diabetes mellitus is a major health issue that has posed a significant challenge over the years. is a well-known plant that can be potentially used to treat this disease. Therefore, this study aimed to evaluate the inhibitory effect of its root, stem bark, leaves, and flower extracts on alpha-glucosidase using an in vitro inhibition assay to isolate the bioactive compounds and determine their levels in the samples.

Antihypertensive Activity of Combination of (Ten.) V. Steenis and L. Leaves on Epinephrine Induced Male Wistar Rat.

In Indonesia, hypertension is a condition that can lead to death through stroke and TB. Herbs have traditionally been used in Indonesia as an alternative medicine for lowering blood pressure. The leaves of and have been investigated for their antihypertensive potential.

Secondary metabolite compounds from Sida genus and their bioactivity.

Plants are the key source for the production of novel therapeutic products for new medicines. The biological properties of the plant species used world wide are mainly accountable for their secondary metabolites obtained from plants. The goal of this analysis is to summarize the chemical composition and biological effects of the genus Sida (Malvaceae) to identify potential research opportunities.

Molecular modeling for potential cathepsin L inhibitor identification as new anti-photoaging agents from tropical medicinal plants.

Ultraviolet exposure can cause photoaging toward the human skin which is begun by the inflammation on the exposure area, also resulting in activation of a degradative enzyme cathepsin L. This enzyme is one of the interesting novel therapeutic targets for antiaging agents. Three plants, named Kleinhovia hospita, Aleurites moluccana, and Centella asiatica, are well-known in the tropical region as anti-inflammatory herbs.

Isolation and Characterization of Phenylpropanoid and Lignan Compounds from [L.] Kunth with Estrogenic Activities.

Extracts of [L.] Kunth have previously been demonstrated to have in vivo estrogenic-like effects, thereby functioning as an anti-osteoporotic agent. However, the compounds responsible for these effects have not yet been determined.

Isolation of 5,7-Dihydroxy, 6,8-Dimethyl Flavanone from with Its Antioxidant and Xanthine Oxidase Inhibitor Activities.

Background: Burm.f. Alston (water apple) belonging to Myrtaceae family was originated from tropical areas.

Fractionation using adsorptive macroporous resin HPD-600 enhances antioxidant activity of L. seed hard shell extract.

In this study, antioxidant activities and identification of the bioactive substances in L. (Gg) seed hard shell were evaluated. The seed of L.