[Insanovin aerosol therapy in the treatment of bronchial asthma].

Sixty-seven patients with bronchial asthma treated with the bronchodilator insanovin for 4 weeks were followed up. The efficiency of aerosol therapy with insanovin as the basic agent was determined by the time course of changes in the clinical manifestations of the disease, in external respiratory functional and immunological parameters. In patients with first-degree bronchial obstruction, 2 weeks of aerosol therapy were sufficient to normalize the clinical manifestations of the diseases and external respiratory functional and immunological parameters.

[Humoral and cellular immunity in meningitis of various etiology].

The parameters of humoral and cellular immunity were studied in patients with meningitis due to tuberculosis and other diseases. Peripheral blood and spinal fluid were measured in 91 and 76 patients with tuberculous meningitis, in 75 and 59 with purulent meningitis, and in 54 and 33 with serous meningitis, respectively. Comparing assessment of the findings revealed profound changes in the content of T lymphocytes and their subpopulations.

[In vitro study of the modulating effect of antitubercular agents on the rosette formation response in patients with pulmonary tuberculosis].

The wide medical application of new highly active antituberculous agents (ATA) having a definite mechanism of action on immunological homeostasis makes pharmacological regulation of immunological responses real in patients with pulmonary tuberculosis. The purpose of this study was to examine the effect of major ATA on the body's immunological responsiveness in vitro, i.e.

[Luminol-dependent neutrophilic chemiluminescence in patients with chronic nonspecific lung diseases].

To assess the prognostic value of neutrophilic chemiluminescence, an examination was made of 68 patients with chronic bronchitis, 96 with bronchial asthma, and 34 apparently healthy individuals. Metabolic activity was determined by spontaneous and induced chemiluminescence in the whole blood and neutrophilic samples (the procedure being given). Patients with chronic bronchitis or bronchial asthma were found to have much higher metabolic activity in the neutrophils.

[Comparative analysis of the results of spinal fluid microbiological study in children and adults who suffered from tuberculous meningitis].

An examination was made of 133 children and 89 adults, aged 3 to 60 years, who had admitted for suspected tuberculous meningitis. The diagnosis of tuberculous meningitis was established in 113 children and 79 adults. In the remaining 20 ill children and 10 adult patients, tuberculous etiology of the disease was rejected.

[The effect of the ultraphonophoesis of deresinated naphthalan in patients with a history of exudative pleurisy].

Clinicoimmunological comparisons suggest the conclusion on positive effect of deresinated naphthalan phonophoresis when given early in the course of inpatient combined treatment of exudative pleurisy. The response was noted in the trend of clinical and immunological characteristics of T- and B-cell immunity.

[Gene geography of hereditary glucose-6-phosphate dehydrogenase deficiency and pulmonary tuberculosis in Azerbaijan].

A comparative study of the detection rate for glucose-6-phosphate dehydrogenase (G-6-PDH) deficiency was carried out among the indigenous population of different regions of Azerbaijan with epidemiologic tuberculosis situation. A screening comprising the Bernstein test (for revealing enzymopathy in the erythroid series cells) and the NS test (for revealing enzyme deficiency in leukocytes) was conducted to find hereditary G-6-PDH deficiency. A comparison of the epidemiologic parameters of the pertinent regions revealed the correlation between the detection rate for G-6-PDH deficiency in the republican regions and the epidemiologic tuberculosis situation.

[Clinical symptoms and course of tuberculous meningitis in children: isolation of L-forms from the cerebrospinal fluid].

The paper deals with the clinical symptoms and course of childhood tuberculous meningitis which were associated with M. tuberculosis form detected in the cerebrospinal fluid. It was found that with the bacterial forms of the agent in the liquor, the disease is characterized by an acute onset and rapid development of inflammatory changes.

[Clinico-immunologic characteristics of patients with pulmonary tuberculosis, psychic diseases and a congenital glucose-6-phosphate dehydrogenase deficiency].

Clinical and immunological characteristics of the tuberculosis process in patients with mental diseases and congenital deficiency of glucose-6-phosphate dehydrogenase were investigated. Enzymopathy was detected in 34 (8.9 per cent) out of 382 patients subjected to the investigation.

[Pulmonary tuberculosis in patients with hereditary glucose-6-phosphate dehydrogenase deficiency].

A study was made of the occurrence of glucose-6-phosphate dehydrogenase (G-6-PDH) deficiency among patients with lung tuberculosis including those suffering from mental diseases (alcoholism or schizophrenia). In Azerbaijani patients, the rate of G-6-PDH demonstration was higher as compared to that among the healthy population. On combined lung tuberculosis and alcoholism the rate of that abnormality demonstration increased whereas on associated lung tuberculosis and schizophrenia, it slightly decreased.

The efficiency of chemotherapy with immunomodulators for patients with destructive lung tuberculosis.

Immunomodulators are to be prescribed to tuberculous patients in accordance with clinical and immunologic indices for 2 months. Taking into account that levamisol in dose 100 mg/24 hours is well tolerated by the patients and is as efficient as in the dose 150 mg/24 hours it is recommended to use this agent in dose 100 mg/24 hours three times a week. As it became evident from the clinical-roentgenologic, bacteriologic and immunologic data diuciphon is better tolerated by the patients and more efficient than levamisol.

[Circulating immune complexes and mycobacterial antigens in the blood of pulmonary tuberculosis patients].

The level of circulating immune complexes (CIC) in the sera of patients with fibrocavernous tuberculosis and infiltrative tuberculosis has been found to be correlated with the dissociation and level of mycobacterial antigens contained in CIC. Successful chemotherapy results in the normalization of all the characteristics under study.

[Differential diagnosis of tuberculosis and other diseases affecting the middle lobe of the lung (lingular lobe)].

Based on data resulting from clinical, laboratory, bronchological and radiological correlations investigated in 102 patients with affections involving the median pulmonary lobe (the lingula), the author concluded that no characteristic symptoms can be evidenced, suggesting lesions of the anterior pulmonary areas. The major role in establishing the characteristics of the lesion in this area falls to the radio-bronchological investigation performed specifically for this. According to the radiological aspects the author identified 6 types of broncho-stenotic syndromes involving the median pulmonary lobe, but he stresses that in view of making an etiologic diagnosis the bronchologic investigation, and the cytohistologic study of bioptic material are of major importance.