Role of Antiplatelets and Anticoagulation Therapies in Pregnancy.

Thrombosis is an important cause of morbidity and mortality worldwide. Pregnancy is a hypercoagulable state, and thrombotic complications in pregnancy are a major cause of maternal and fetal morbidity and mortality. Current guidelines support the selective use of aspirin, heparin, and warfarin in pregnant women.

Delivering bad or difficult news. An innovative simulation-based education approach to prepare interdisciplinary fellowships.

Background: There is limited data on the effectiveness of training interventions to improve the delivery of bad news.

Methods: This preliminary research included pre-post assessments and an open-ended survey to evaluate the effectiveness and perceived value of training on delivering bad news for 26 first- and second-year fellows from five adult and pediatric fellowship programs.

Results: There was a significant increase in faculty assessment scores (34.

A comparison of Doppler waveform parameters versus flow-mediated vascular dilation of the brachial artery in pregnant women.

Objective: Flow mediated dilation of the brachial artery is impaired with endothelial dysfunction. We previously identified that brachial artery waveforms were changed in preeclamptic women. We therefore sought to compare Doppler waveform analysis with flow mediated vascular dilation (FMVD) measurements in pregnant women.

Improving antenatal prediction of small-for-gestational-age neonates by using customized versus population-based reference standards.

Objectives: The purpose of this study was to evaluate whether the use of customized fetal reference standards improves the prenatal detection of intrauterine growth restriction.

Methods: We conducted a retrospective cohort study. Singleton pregnancies with a diagnosis of a small-for-gestational-age (SGA) fetus based on the in utero reference standard of Hadlock et al (Am J Obstet Gynecol 1985; 151:333-337; Radiology 1991; 181:129-133) were identified from our ultrasound database, and customized percentiles were calculated by adjusting for maternal height, weight, ethnicity, parity, and sex.

Karyotype of miscarriages in relation to maternal weight.

Background: Obesity has been identified as a risk factor for spontaneous miscarriage although the mechanism is unclear. The purpose of this study is to better understand the effect of obesity on early pregnancy success by examining the cytogenetic results of miscarriages in women with normal and elevated body mass index (BMI).

Methods: We conducted a retrospective case-control study in an academic infertility practice.