Detection of drug effects on gastric emptying and contractility using a wireless motility capsule.

Background: A wireless motility capsule is a new method for ambulatory assessment of transit times and motility throughout the gastrointestinal tract. The objective of this study was to evaluate the ability of a wireless motility capsule to detect drug effects on gastric emptying time (GET) and gastric contractility.

Methods: 15 healthy adults were administered in random order saline, erythromycin IV 150 mg, or morphine IV 0.