Peculiarities of clinical signs, course and treatment of musculoskeletal system lesions in post-COVID syndrome.

Introduction: Post-COVID syndrome (PCS) is a frequent phenomenon of patients who have suffered from an acute attack of COVID-19 infection, and it is characterized by a wide range of symptoms from different organs and systems including the musculoskeletal system (MSS). However, peculiarities of MSS lesions have not been sufficiently studied to date, in particular, in the aspect of the therapeutic process. We aimed to investigate peculiarities of MSS lesions in patients with PCS.

SPICES: MODERN VIEWS ON THE APPLICATION THROUGH THE PRISM OF POLY- AND COMORBIDITY OF PATIENTS AND INFECTIOUS PANDEMICS (LITERATURE REVIEW AND DISCUSSION).

Objective: The aim: To substantiate the need of wider use of species in dietician rehabilitation of patients with poly- and comorbidity, postcovid syndrome based on the analysis of the latest scientific achievements with the study of their pharmacological properties.

Patients And Methods: Materials and methods: The information search in printed and electronic editions, search scientific bases with application of methods of the analysis, comparison and generalization of information data is carried out.

Conclusion: Conclusions: New scientific data on the pharmacological properties of spices give grounds to use them more widely in the rehabilitation of patients with poly- and comorbidities and infectious processes.

Glutathione-S-transferases genes-promising predictors of hepatic dysfunction.

One of the most commonly known genes involved in chronic diffuse liver diseases pathogenesis are genes that encodes the synthesis of glutathione-S-transferase (GST), known as the second phase enzyme detoxification system that protects against endogenous oxidative stress and exogenous toxins, through catalisation of glutathione sulfuric groups conjugation and decontamination of lipid and deoxyribonucleic acid oxidation products. The group of GST enzymes consists of cytosolic, mitochondrial and microsomal fractions. Recently, eight classes of soluble cytoplasmic isoforms of GST enzymes are widely known: α-, ζ-, θ-, κ-, μ-, π-, σ-, and ω-.