Publications by authors named "Inmaculada Jimenez-Moleon"
Arthritis Rheumatol
June 2021
Article Synopsis
- - The study aims to improve the classification and treatment of systemic autoimmune diseases by identifying molecular clusters, moving beyond traditional clinical diagnosis methods.
- - Researchers analyzed blood samples from 955 patients and 267 healthy controls, discovering four distinct clusters: three linked to inflammatory responses and one related to low disease activity associated with healthy controls.
- - The findings suggest that these molecular clusters are stable over time and can aid in understanding disease mechanisms and improving treatment strategies, potentially changing how systemic autoimmune diseases are approached in clinical settings.
Medicine (Baltimore)
September 2015
Article Synopsis
- Anakinra (ANK), an interleukin-1 receptor antagonist, was evaluated for its effectiveness in treating adult-onset Still's disease (AOSD), particularly for patients resistant to standard therapies and other biologics.*
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- A study involving 41 AOSD patients showed rapid improvements in clinical symptoms and laboratory results after starting ANK, with significant reductions in fever, joint pain, anemia, and lymphadenopathy over a year.*
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- While ANK proved successful for many, some joint manifestations remained challenging to treat, and the main side effects included skin issues, mild leukopenia, and various infections.*
