Publications by authors named "Inmaculada Granero Cremades"
Article Synopsis
- Exhaled breath tests (BTs) are used to diagnose fructose and lactose intolerance as well as small intestine bacterial overgrowth (SIBO) but their reliability for detecting SIBO is not well established.
- This study examined the accuracy of fructose and lactose BTs compared to traditional SIBO tests in recognizing SIBO and identifying intestinal methanogen overgrowth (IMO).
- Results indicated that lactose BTs were more specific for SIBO detection, while fructose BTs were more sensitive, but they had a 27% false negative rate for IMO, showing inconsistency in results between the two types of tests.
Epigenetic changes such as DNA methylation were observed in drug-resistant temporal lobe epilepsy (DR-TLE), a disease that affects 25-30% of epilepsy patients. The main objective is to simultaneously describe DNA methylation patterns associated with DR-TLE in hippocampus, amygdala, surrounding cortex to the epileptogenic zone (SCEZ), and peripheral blood. An Illumina Infinium MethylationEPIC BeadChip array was performed in 19 DR-TLE patients and 10 postmortem non-epileptic controls.
View Article and Find Full Text PDFNeuronal and astrocytic tetraploidy is increased in drug-resistant epilepsy.
Ancor Sanz-García Patricia Sánchez-Jiménez Inmaculada Granero-Cremades María de Toledo Paloma Pulido
Neuropathol Appl Neurobiol
February 2023
Aims: Epilepsy is one of the most prevalent neurological diseases. A third of patients with epilepsy remain drug-resistant. The exact aetiology of drug-resistant epilepsy (DRE) is still unknown.
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