Publications by authors named "Inmaculada Alia"
Article Synopsis
- The study investigates the impact of exacerbations of Chronic Obstructive Pulmonary Disease (ECOPD) on global mortality and hospital readmission rates after hospitalization.
- The analysis included data from 65,945 COPD patients, revealing a 6.2% in-hospital mortality rate and significant post-discharge mortality and readmission rates at various intervals.
- Researchers emphasize the need for standardized management of ECOPD and suggest that policymakers prioritize funding for effective therapies to reduce the incidence of recurrent hospitalizations.
Introduction: Previous reports have shown very high mortality among hemodialyisis patients. Our goal was to analyze the mortality of patients in the Renal Registry of Patients who remained exclusively on hemodialysis treatment.
Methods: The cohort of patients who started treatment in the community of Castilla-La Mancha between 2010 and 2012 and remained on hemodialysis treatment was analysed until the end of 2017.
Background: Randomized trials assessing the effect of systemic corticosteroids on chronic obstructive pulmonary disease (COPD) exacerbations excluded patients who were mechanically ventilated or admitted to the intensive care unit (ICU). Critically ill patients constitute a population of persons who are prone to develop complications that are potentially associated with the use of corticosteroids (eg, infections, hyperglycemia, ICU-acquired paresis) that could prolong the duration of mechanical ventilation and even increase mortality.
Methods: A double-blind placebo-controlled trial was conducted to evaluate the efficacy and safety of systemic corticosteroid treatment in patients with an exacerbation of COPD who were receiving ventilatory support (invasive or noninvasive mechanical ventilation).
Purpose: Despite the evidence, the use of selective decontamination of the digestive tract (SDD) remains controversial, largely because of concerns that it may promote the emergence of antibiotic-resistant strains. The purpose of this study was to evaluate the long-term incidence of carriage of antibiotic-resistant bacteria (ARB), its clinical impact on developing infections and to explore risk factors of acquiring resistance.
Methods: This study was conducted in one 18-bed medical-surgical intensive care unit (ICU).
Objective: The aim of this study was to assess the efficacy and safety of enteral vancomycin in controlling MRSA endemicity in an intensive care burn unit.
Summary Background Data: MRSA is a serious clinical and epidemiologic problem. It is not uncommon that the traditional maneuvers, detection and isolation of carriers, fail to control endemicity due to MRSA.
Study Objective: Noninvasive mechanical ventilation (NIMV) is beneficial for patients with acute respiratory failure (ARF) when added to medical treatment. However, its role as an alternative to conventional mechanical ventilation (CMV) remains controversial. Our aim was to compare the efficacy and resource consumption of NIMV against CMV in patients with ARF.
View Article and Find Full Text PDFObjective: To determine the usual practice for setting tidal volume and other ventilatory parameters in patients with acute respiratory distress syndrome (ARDS) in the late 1990s and to determine the independent effects of these practices on intensive care unit mortality.
Design: Subanalysis of a prospective observational study. Multivariable logistic regression was used to analyze the effects of ventilatory management on mortality.
Background: The American-European Consensus Conference definition for the acute respiratory distress syndrome (ARDS) has never been validated.
Objective: To compare clinical criteria for ARDS with autopsy findings.
Design: Independent comparison of autopsy findings with clinical characteristics retrospectively abstracted from medical records.
Background: The need for reintubation after extubation and discontinuation of mechanical ventilation is not uncommon and is associated with increased mortality. Noninvasive positive-pressure ventilation has been suggested as a promising therapy for patients with respiratory failure after extubation, but a single-center, randomized trial recently found no benefit. We conducted a multicenter, randomized trial to evaluate the effect of noninvasive positive-pressure ventilation on mortality in this clinical setting.
View Article and Find Full Text PDFObjective: To determine the threshold of age that best discriminates the survival of mechanically ventilated patients and to estimate the outcome of mechanically ventilated older patients.
Design: International prospective cohort study.
Setting: Three hundred sixty-one intensive care units from 20 countries.
Objective: To determine the incidence, risk factors, and outcome of barotrauma in a cohort of mechanically ventilated patients where limited tidal volumes and airway pressures were used.
Design And Setting: Prospective cohort of 361 intensive care units from 20 countries.
Patients And Participants: A total of 5183 patients mechanically ventilated for more than 12 h.
Context: The outcome of patients receiving mechanical ventilation for particular indications has been studied, but the outcome in a large number of unselected, heterogeneous patients has not been reported.
Objective: To determine the survival of patients receiving mechanical ventilation and the relative importance of factors influencing survival.
Design, Setting, And Subjects: Prospective cohort of consecutive adult patients admitted to 361 intensive care units who received mechanical ventilation for more than 12 hours between March 1, 1998, and March 31, 1998.