Publications by authors named "Ingrid de Campos Albuquerque"
High prevalence of hepatitis B virus and low vaccine response in children and adolescents in Northeastern Brazil.
Rev Inst Med Trop Sao Paulo
April 2023
Article Synopsis
- * Key factors linked to HBV infection include residing in specific municipalities, living in rural areas, being aged 13-15, and using illicit drugs.
- * The study highlights inadequate vaccination coverage, with only 38.9% of vaccinated individuals developing protective antibodies, signaling a need for improved preventative measures and vaccine quality in these communities.
Introduction And Objectives: Research has shown that hepatitis B (HBV) and Delta virus (HDV) are a worldwide public health problem. This study aims to estimate the prevalence rates of HBV and HDV infection in five municipalities of Maranhão, Northeastern Brazil.
Materials And Methods: A total sample between 3856 and 4000 individuals.
Mutations in the a determinant of S gene may develop co-existence of hepatitis B surface antigen (HBsAg) and antibodies to HBsAg (anti-HBs) in the serum of infected hepatitis B virus (HBV) individuals. Mutations in this region may change the antigenicity of HBsAg, which in turn, lead to escape of neutralizing action of anti-HBs antibodies. This study identified individuals with concomitant HBsAg and anti-HBs serological markers in individuals of Maranhão, Northeastern Brazil.
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