Publications by authors named "Ingrid Platania"

Article Synopsis
  • Venous thromboembolism (VTE) is a complex disease influenced by multiple factors, particularly inflammation, which can lead to a pro-thrombotic state.
  • Anticoagulant medications, like low-molecular-weight heparins (LMWH) and direct oral anticoagulants (DOACs), are key treatments for VTE, with LMWH also lowering inflammatory markers like interleukin (IL)-6.
  • A study found that DOACs reduced IL-6 levels in patients with deep vein thrombosis (DVT) compared to controls, suggesting that their anti-inflammatory effects may contribute to their treatment efficacy in VTE.
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Reduction of hazard risk of cerebral ischemic event (stroke, transient ischemic attack (TIA)) represents the hard point to be achieved from primary or secondary preventive strategy in the best clinical practice. However, results from clinical trials, recommendations, guidelines, systematic review, expert opinions, and meta-analysis debated on the optimal pharmacotherapy to achieve the objective. Aspirin and a number of antiplatelet agents, alone or in combination, have been considered from large trials focused on stroke prevention.

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Arterial hypertension (AH) is a major risk factor for chronic kidney disease (CKD). However, whether AH maintains this role in the development of CKD in elderly patients with aortic stenosis (AS) or whether transaortic gradient influences CKD remains unclear. Consecutive hospitalized patients were prospectively recruited to evaluate the relationship between AS and CKD.

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