Publications by authors named "Ingrid M de Zwart"

Purpose: To determine the accuracy of magnetic resonance imaging (MRI) volume scans: 1) to measure known meal volumes in vitro, and 2) to compare volume changes in response to a meal measured with the barostat with those measured with MRI in vivo.

Materials And Methods: Polyethylene bags were filled with known volumes and MRI volume scans were performed to determine the accuracy of the volume measurements. Barostat measurements and MRI volume scans were performed simultaneously in 14 healthy subjects before and up to 90 minutes after ingestion of a liquid meal.

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Background: Evaluation of gastric physiology (gastric emptying and motility) is important for the diagnosis of disturbances such as functional dyspepsia. MRI is a non-invasive technique that allows simultaneous registration of gastric emptying and motility.

Aim: To provide an overview of the literature of studies that used MRI as a tool for evaluation of gastric function in both research and clinical settings.

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The barostat is considered the gold standard for evaluation of proximal gastric motility especially for the accommodation response to a meal. The procedure is invasive because it involves the introduction of an intragastric catheter and bag and is not always well tolerated. Moreover, the barostat bag itself may influence motility.

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Measurements of gastric volume and motility with magnetic resonance (MR) imaging were compared with simultaneously performed measurements with a barostat in six healthy volunteers. Three-dimensional volume and two-dimensional dynamic MR images and barostat measurements were obtained at rest. Alterations in gastric volume and motility were induced by means of infusion of glucagon and erythromycin, respectively.

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