Nail Psoriasis: A Systematic Evaluation in 313 Children with Psoriasis.

Background/objectives: Little information is available on the prevalence and clinical aspects of nail involvement in children with psoriasis. The objective of this study was to evaluate the prevalence and clinical aspects of and the risk factors for nail involvement in French children with psoriasis.

Methods: We performed a multicenter, cross-sectional study in 23 French dermatology centers.

Prognostic factors of paraneoplastic pemphigus.

Objective: To identify the prognostic factors of overall survival in a series of patients with paraneoplastic pemphigus (PNP).

Design: Multicenter retrospective cohort study.

Setting: Twenty-seven dermatology departments in France.

Corticosteroid treatment for melanoma-associated retinopathy: effect on visual acuity and electrophysiologic findings.

Background: Visual disturbance in the course of melanoma is rare. Specific localized metastases and drug toxic effects are frequently the cause. Recognition of a retinopathy raises several questions when the diagnosis of melanoma-associated retinopathy (MAR) can be confirmed.

Eosinophilic leukemia associated with t(2;5)(p23;q31).

Chromosomal aberrations have been reported in most malignant hematopoietic disorders such as acute or chronic myeloid leukemia, acute lymphoid leukemia, and myelodysplastic syndromes. Eosinophilic leukemia is a rare hematologic malignancy difficult to distinguish from other forms of idiopathic hypereosinophilic syndrome, so that the diagnosis is often made by exclusion, unless cytogenetic abnormalities can be demonstrated in bone marrow cells. We describe a patient with eosinophilic leukemia whose cytogenetic study shows a t(2;5)(p23;q31).