Factors affecting the efficacy of peripheral blood progenitor cells collections by large-volume leukaphereses with standardized processing volumes.

Background: Peripheral blood progenitor cell (PBPC) collections should be safe and efficient. Therefore, the influence and risk factors in large-volume leukaphereses (LVL) with standardized blood volumes was investigated.

Study Design And Methods: In a total of 724 autologous LVL performed at our center, either 4x or 6x the patient's blood volume (PBV) was processed.