Publications by authors named "Ingo Krech"
Front Pharmacol
February 2014
Article Synopsis
- Tenecteplase is a crucial treatment for acute myocardial infarction, with both Metalyse(®) and a biosimilar called Elaxim(®) available in India.
- Research shows that Elaxim has less clot lysis activity and a different biochemical profile compared to Metalyse, including variations in glycosylation and purity.
- These differences raise concerns about whether Elaxim should be classified as a true "biosimilar" of Metalyse, especially without comparative clinical data to support its efficacy and safety.
