Publications by authors named "Ingo Koenigs"

Background: Predicting burn-related mortality is vital for family counseling, triage, and resource allocation. Several of the burn-specific mortality prediction scores have been developed, including the Abbreviated Burn Severity Index (ABSI) in 1982. However, these scores are not tested for accuracy to support contemporary estimates of the global burden of burn injury.

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  • Fluid resuscitation is crucial for managing severe burns in pediatric patients, with the Parkland formula commonly used to calculate fluid needs.
  • A study analyzed data from the German Burn Registry to assess the impact of fluid volume deviations from the Parkland formula on hospital stays and in-hospital mortality in children under 16 with significant thermal injuries.
  • Findings indicated that most patients (86.5%) received less fluid than recommended; a slight increase in fluid volume correlated with longer hospital stays, suggesting potential benefits of restricted fluid resuscitation.
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Purpose: In pediatric population, large soft tissue defects occur in avulsion injuries. In addition to the challenges of primary surgical therapy, elasticity, appearance and function of the scar in children are of crucial importance, especially in the context of body growth. So far various flaps, plasties, skin grafts and dermal substitutes have become established, although infections and skin shrinkage remain challenging.

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  • Increasing antibiotic resistance is a global issue, particularly concerning multidrug resistant organisms (MDRO) in children upon hospital admission, which remains understudied.
  • A study in Hamburg assessed MDRO prevalence in 3,964 children, finding a total carriage rate of 4.31%, with the highest rates for multidrug-resistant Gram-negative bacteria (MRGN) at 3.64%.
  • Key risk factors for MDRO carriage included a history of MRGN, chronic health conditions, recent antibiotic therapy, living in care facilities, and refugee status, suggesting that a risk-factor-based screening approach could improve detection rates during hospital admissions.
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Background: Currently, a range of different antibiotics are administered perioperatively during appendectomy surgery in the pediatric population. One reason for the lack of a uniform treatment regimen is the paucity of large studies on microbiologic data and susceptibility patterns.

Methods: A retrospective, monocentric study on antibiotic susceptibility, including 1258 pediatric patients undergoing appendectomy from 2012 to 2020 was performed.

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  • - Healthcare workers, especially those in pediatrics, are at high risk for COVID-19 due to potential exposure from asymptomatic children, but no studies focused on this group in Germany prior to this research.
  • - Researchers tested 619 staff members at a children's hospital for SARS-CoV-2 IgG antibodies and collected data on their perceived infection risk; the seroprevalence rate was found to be only 0.325%.
  • - Self-perceived risk of infection decreased with age, and individuals who had symptoms were more likely to believe they had been infected, but overall, the self-perceived risk often exceeded actual risk levels.
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It is not only important for counseling purposes and for healthcare management. This study investigates the prediction accuracy of an artificial intelligence (AI)-based approach and a linear model. The heuristic expecting 1 day of stay per percentage of total body surface area (TBSA) serves as the performance benchmark.

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Objectives: The Abbreviated Burn Severity Index (ABSI) is a widely used and simple score to predict mortality after burn injuries. On the one hand, significant improvements in intensive care management and surgical treatment result in an increased survival rate. On the other hand, the aging population might lead to an increased injury-related mortality rate.

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Burn disasters present a challenge not only to burn centers but the entire healthcare system. Most burn centers worldwide are unprepared to deal with a burn disaster as it is an uncommon event. We investigated the status of burn center preparedness in German-speaking countries to respond to a burn disaster.

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NexoBrid (NXB) has been proven to be an effective selective enzymatic debridement agent in adults. This manuscript presents the combined clinical trial experience with NXB in children. Hundred and ten children aged 0.

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Background: Thermal injuries are a frequent cause of accidents within the pediatric population that may result in long periods of hospitalization as well as severe physical and mental impairment and lifelong consequences. Especially in infants, burns caused by scalding are the most common cause of injury. Beside accidental injuries, intential burns may also occur.

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Objective: The purpose of this observational, multi-center study was to reveal epidemiologic, etiological and clinical aspects of hospitalized children with thermal injuries in Germany and Austria and the workup of a renewed web-based pediatric burn registry.

Methods: From 2006 to 2015, comprehensive patient data of thermally injured children in Germany and Austria were collected prospectively. Retrospective analysis of age, gender, mechanism of injury, total body surface area burned, way of admission and length of stay was performed, followed by the comparative analysis between designated burn centers and other pediatric hospitals.

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Pressure sores (PSs) and wounds in immunocompromised children are rather rare conditions. No doubt, their management is often complex and difficult, even for experienced pediatric plastic surgeons. As there are no algorithms for standard care, the therapeutic approach is individual.

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