Marathon running leads to partial exhaustion of ROS-generating capacity in leukocytes.

Purpose: The aim of the present study was to investigate the changes occurring in leukocyte levels of reactive oxygen species (ROS) and total blood plasma antioxidant capacity (TAS) as a result of a marathon/half-marathon race.

Methods: Fourteen men participating in the Oslo Marathon 2000 and 8 women and 8 men participating in the Oslo Half-Marathon 2001 were recruited to the study. Flow cytometry and the ROS-sensitive probe dihydroethidium (DHE) were used to study the intracellular levels of ROS in circulating leukocytes.

Platelet-platelet and platelet-leukocyte interactions induced by outer membrane vesicles from N. meningitidis.

Unlabelled: A large part of native meningococcal lipopolysaccharide (LPS), i.e., LPS integrated in the outer cell membrane, is released in the form of 'blebs' from surplus outer membrane material.