Substantiating the Short Burst Duration in Cortical Myoclonus.

Background: Myoclonus is characterized by involuntary, shock-like movements, of which cortical (CM) and non-cortical myoclonus (NCM) are most common. Electrophysiology can help differentiate between these subtypes; however, the diagnostic value of several features is largely unknown.

Objective: This study aims to determine the diagnostic value of the burst duration in distinguishing CM and NCM.

Digital Health Technology Use Across Socioeconomic Groups Prior to and During the COVID-19 Pandemic: Panel Study.

Background: Digital technologies have become more important in the health care sector in the past decades. This transition from conventional to digital health care has been accelerated by the impact of the COVID-19 pandemic, which poses the risk of creating a "digital divide," inadvertently placing those who are older, economically disadvantaged, and have a lower level of education at a disadvantage.

Objective: This study focuses on the influence of socioeconomic factors on the adoption of digital health technology in the Frisian population and how this relation is affected by the COVID-19 pandemic.

Eye movement disorders in inborn errors of metabolism: A quantitative analysis of 37 patients.

Inborn errors of metabolism are genetic disorders that need to be recognized as early as possible because treatment may be available. In late-onset forms, core symptoms are movement disorders, psychiatric symptoms, and cognitive impairment. Eye movement disorders are considered to be frequent too, although specific knowledge is lacking.

Next move in movement disorders (NEMO): developing a computer-aided classification tool for hyperkinetic movement disorders.

Introduction: Our aim is to develop a novel approach to hyperkinetic movement disorder classification, that combines clinical information, electromyography, accelerometry and video in a computer-aided classification tool. We see this as the next step towards rapid and accurate phenotype classification, the cornerstone of both the diagnostic and treatment process.

Methods And Analysis: The Next Move in Movement Disorders (NEMO) study is a cross-sectional study at Expertise Centre Movement Disorders Groningen, University Medical Centre Groningen.

Task constraints act at the level of synergies and at the level of end-effector kinematics in manual reaching and manual lateral interception.

To coordinate the redundant degrees of freedom (DOF) in the action system, synergies are often proposed. Synergies organize DOF in temporary task-specific units emerging from interactions among task, organism, and environmental constraints. We examined whether task constraints affect synergies, end-effector kinematics, or both.

Comparing Different Methods to Create a Linear Model for Uncontrolled Manifold Analysis.

An essential step in uncontrolled manifold analysis is creating a linear model that relates changes in elemental variables to changes in performance variables. Such linear models are usually created by means of an analytical method. However, a multiple regression analysis is also suggested.

The development of consistency and flexibility in manual pointing during middle childhood.

Goal-directed actions become truly functional and skilled when they are consistent yet flexible. In manual pointing, end-effector consistency is characterized by the end position of the index fingertip, whereas flexibility in movement execution is captured by the use of abundant arm-joint configurations not affecting the index finger end position. Because adults have been shown to exploit their system's flexibility in challenging conditions, we wondered whether during middle childhood children are already able to exploit motor flexibility when demanded by the situation.

Does practicing a wide range of joint angle configurations lead to higher flexibility in a manual obstacle-avoidance target-pointing task?

Flexibility in motor actions can be defined as variability in the use of degrees of freedom (e.g., joint angles in the arm) over repetitions while keeping performance (e.